ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2014
Septal penetration in iodine-123 metaiodobenzylguanidine cardiac sympathetic imaging using a medium-energy collimator.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors at 2 institutions in 1 country.
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Abstract
backgroundSeptal penetration of high-energy photons affects the estimation of the heart-to-mediastinum (H/M) ratio in cardiac (123)I-metaiodobenzylguanidine (MIBG) imaging, and the use of a medium-energy (ME) collimator has been shown to improve quantitative accuracy. We investigated the effect of septal penetration on the estimation of H/M ratios using an ME collimator. METHODS AND
resultsPoint sources of (99m)Tc and (123)I were imaged using various collimators, which indicated that the effect of high-energy photons with the ME collimator was relatively small but larger than that with the high-energy (HE) collimator. Four hours after (123)I-MIBG injection, 20 patients underwent planar anterior chest imaging by different methods in succession. The ME collimator gave lower H/M ratios (mean 2.52) than the HE collimator (2.57), indicating influence of septal penetration in the ME collimator; however, the difference was limited. Although narrowing the energy window from 20% (2.51) to 15% (2.54) increased the H/M ratios in imaging with the ME collimator, the difference was quite limited.
conclusionsSeptal penetration affects the estimation of the H/M ratios using an ME collimator; however, this influence is small and would not have clinical significance.
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