ArticleJournal of biomedical optics2013
Determination of optical properties by interstitial white light spectroscopy using a custom fiber optic probe.
Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- First in human measurements of abscess cavity optical properties and methylene blue uptake prior to photodynamic therapy byJournal of biomedical optics · 2024Article
- Integrating clinical access limitations into iPDT treatment planning with PDT-SPACE.Biomedical optics express · 2023Article
- Diffuse reflection spectroscopy at the fingertip: design and performance of a compact side-firing probe for tissue discrimination during colorectal cancer surgery.Biomedical optics express · 2023Article
- Optical property recovery with spatially-resolved diffuse reflectance at short source-detector separations using a compact fiber-optic probe.Biomedical optics express · 2021Article
- Article
- Recovery of optical properties using interstitial cylindrical diffusers as source and detector fibers.Journal of biomedical optics · 2016Article
- Cylindrical diffuser axial detection profile is dependent on fiber design.Journal of biomedical optics · 2015Article
- Comparison of flat cleaved and cylindrical diffusing fibers as treatment sources for interstitial photodynamic therapy.Medical physics · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We demonstrate interstitial recovery of absorption and scattering coefficients using a custom optical probe and a Monte Carlo (MC)-based recovery algorithm. The probe consists of six side-firing spectroscopy fibers contained in a 1.1-mm outer diameter cladding, with each fiber having a different axial and angular position on the probe. Broadband white light is delivered by one of the fibers and is detected steady-state by the remaining fibers. These spatially and spectrally resolved data are analyzed using a MC-based fitting algorithm in order to extract the local optical properties. The technique was verified in tissue-simulating phantoms consisting of Intralipid-20% as a scatterer and either manganese meso-tetra (4-sulfanatophenyl) porphine or intact human erythrocytes as an absorber. Absorption coefficients were recovered with a mean error of 9% and scattering coefficients were recovered with a mean error of 19%, whereas the hemoglobin oxygen saturation was recovered with a mean error of 12%. These results demonstrate the feasibility of optical property recovery for situations in which surface-contact spectroscopy is not a possibility, and where only a single probe can be inserted into the tissue.
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Registered trials
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