ArticleJournal of exposure science & environmental epidemiology2014
Serum TCDD and TEQ concentrations among Seveso women, 20 years after the explosion.
Article in Journal of exposure science & environmental epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 30 citations in OpenAlex.
- Serum Dioxin Levels in a Subset of Participants of the East Palestine, Ohio Train Derailment Health Tracking Study.Environmental science & technology letters · 2024Article
- Uncovering Evidence: Associations between Environmental Contaminants and Disparities in Women's Health.International journal of environmental research and public health · 2022Review
- Dioxin exposure associated with fecundability and infertility in mothers and daughters of Seveso, Italy.Human reproduction (Oxford, England) · 2021Article
- Age at menarche in Seveso daughters exposed in utero to 2,3,7,8-tetrachlorodibenzo-p-dioxin.Environmental epidemiology (Philadelphia, Pa.) · 2020Article
- Prenatal dioxin exposure and thyroid hormone levels in the Seveso second generation study.Environmental research · 2020Article
- Prenatal dioxin exposure and glucose metabolism in the Seveso Second Generation study.Environment international · 2020Article
- In utero dioxin exposure and cardiometabolic risk in the Seveso Second Generation Study.International journal of obesity (2005) · 2019Article
- The 2nd to 4th digit length ratio (2D:4D) among children of Seveso women exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.Early human development · 2019Article
- Prenatal dioxin exposure and neuropsychological functioning in the Seveso Second Generation Health Study.International journal of hygiene and environmental health · 2019Article
- The Seveso accident: A look at 40 years of health research and beyond.Environment international · 2018Review
- AHR gene-dioxin interactions and birthweight in the Seveso Second Generation Health Study.International journal of epidemiology · 2018Article
- Risk for animal and human health related to the presence of dioxins and dioxin-like PCBs in feed and food.EFSA journal. European Food Safety Authority · 2018Article
- Neurocognitive and physical functioning in the Seveso Women's Health Study.Environmental research · 2018Article
- Prenatal exposure to TCDD and atopic conditions in the Seveso second generation: a prospective cohort study.Environmental health : a global access science source · 2018Article
- Physiologically based pharmacokinetic toolkit to evaluate environmental exposures: Applications of the dioxin model to study real life exposures.Toxicology and applied pharmacology · 2017Article
- A review of the Texas, USA San Jacinto Superfund site and the deposition of polychlorinated dibenzo-p-dioxins and dibenzofurans in the San Jacinto River and Houston Ship Channel.Environmental science and pollution research international · 2016Review
- Dioxin risk assessment: mechanisms of action and possible toxicity in human health.Environmental science and pollution research international · 2015Review
- Aryl hydrocarbon receptor: Linking environment to immunity.Seminars in immunology · 2015Review
- Integrated ecological risk assessment of dioxin compounds.Environmental science and pollution research international · 2015Review
- Serum dioxin concentrations and thyroid hormone levels in the Seveso Women's Health Study.American journal of epidemiology · 2014Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
The Seveso Women's Health Study (SWHS) is a historical cohort study of the female population residing near Seveso, Italy, on 10 July 1976, when a chemical explosion resulted in the highest known residential exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Individual TCDD concentration was measured in serum collected near the time of the explosion, and in 1996, we collected adequate blood for TCDD and total dioxin toxic equivalent (TEQ) measurement. Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls were measured in 1996 serum for a sample (n=225, 23%) of the SWHS cohort and WHO 2005 TEQs were calculated. We examined characteristics that predict 1996 TCDD concentrations and estimated TCDD elimination half-life over the 20-year period since the explosion. Median lipid-adjusted TCDD and total TEQ concentrations in 1996 serum were 7.3 and 26.2 p.p.t., respectively. Initial 1976 TCDD and age at explosion were the strongest predictors of 1996 TCDD. The TCDD elimination half-life was 7.1 years for women older than 10 years in 1976, but was shorter in those who were younger. Twenty years after the explosion, TCDD concentrations in this SWHS sample, the majority of who were children in 1976, remain elevated relative to background. These data add to the limited data available on TCDD elimination half-life in children.
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