ArticleEmerging health threats journal2011
Can environmental or occupational hazards alter the sex ratio at birth? A systematic review.
Article in Emerging health threats journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.
- Pooled it
- Sex ratio following preconception low-dose aspirin in women with prior pregnancy loss.The Journal of clinical investigation · 2015Trial
- Ambient air pollution and the sex ratio at birth: a systematic review and narrative synthesis.medRxiv : the preprint server for health sciences · 2025Article
- Review
- Association of preconception maternal glucocorticoid concentrations with sex ratio at birth: Evidence from a prospective cohort study.Annals of epidemiology · 2025Article
- Male frequency inEvolutionary applications · 2022Article
- Effects of dioxins on animal spermatogenesis: A state-of-the-art review.Frontiers in reproductive health · 2022Review
- Observable variations in human sex ratio at birth.PLoS computational biology · 2021Article
- Periconceptional Use of Phthalate-Containing Medications and Secondary Sex Ratio.Environmental health perspectives · 2021Article
- Foetal loss and feminine sex ratios at birth in sub-Saharan Africa.Population studies · 2021Article
- A Unifying Theory for Autism: The Pathogenetic Triad as a Theoretical Framework.Frontiers in psychiatry · 2021Article
- Association between occupational testicular radiation exposure and lower male sex ratio of offspring among orthopedic surgeons.PloS one · 2021Article
- Associated factors of secondary sex ratio of offspring in assisted reproductive technology: a cross-sectional study in Jilin Province, China.BMC pregnancy and childbirth · 2020Article
- Change in China's SRB: A Dynamic Spatial Panel Approach.International journal of environmental research and public health · 2020Article
- General and reproductive health outcomes among female greenhouse workers: a comparative study.BMC women's health · 2020Article
- The global male-bias in sex ratio at birth is sustained by the sex ratio genotypes of replacement offspring.Genetica · 2019Article
- Sex ratios at birth vary with environmental harshness but not maternal condition.Scientific reports · 2019Article
- Multigenerational and Transgenerational Effects of Dioxins.International journal of molecular sciences · 2019Review
- Secondary sex ratio in assisted reproduction: an analysis of 1 376 454 treatment cycles performed in the UK.Human reproduction open · 2019Article
- New Biological Insights on X and Y Chromosome-Bearing Spermatozoa.Frontiers in cell and developmental biology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
More than 100 studies have examined whether environmental or occupational exposures of parents affect the sex ratio of their offspring at birth. For this review, we searched Medline and Web of Science using the terms 'sex ratio at birth' and 'sex ratio and exposure' for all dates, and reviewed bibliographies of relevant studies to find additional articles. This review focuses on exposures that have been the subject of at least four studies including polychlorinated biphenyls (PCBs), dioxins, pesticides, lead and other metals, radiation, boron, and g-forces. For paternal exposures, only dioxins and PCBs were consistently associated with sex ratios higher or lower than the expected 1.06. Dioxins were associated with a decreased proportion of male births, whereas PCBs were associated with an increased proportion of male births. There was limited evidence for a decrease in the proportion of male births after paternal exposure to DBCP, lead, methylmercury, non-ionizing radiation, ionizing radiation treatment for childhood cancer, boron, or g-forces. Few studies have found higher or lower sex ratios associated with maternal exposures. Studies in humans and animals have found a reduction in the number of male births associated with lower male fertility, but the mechanism by which environmental hazards might change the sex ratio has not yet been established.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.