SynthesisBMC complementary and alternative medicine2013
Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review.
Synthesis in BMC complementary and alternative medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04023539 (Evaluation of the Effect of Cinnamomum Zeylanicum on Glycemic Levels of Mexican Adult Patients With Type 2 Diabetes at 3 Months), which is not on this map. Cited by 117 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effect of Cinnamomum Zeylanicum on Glycemic Levels of Mexican Adult Patients With Type 2 Diabetes at 3 Months: Randomized Clinical Trial
Who cites it
117 citing papers in PubMed, 1 synthesis or guideline pooled it, 458 citations in OpenAlex.
- Mechanistic and therapeutic insight into the effects of cinnamon in polycystic ovary syndrome: a systematic review.Journal of ovarian research · 2021Pooled it
- Effects of Tabata-style functional training and cinnamon supplementation on army combat fitness test performance, serum irisin, and body composition in military cadets: a randomized controlled trial.Journal of the International Society of Sports Nutrition · 2026Trial
- Spices in a High-Saturated-Fat, High-Carbohydrate Meal Reduce Postprandial Proinflammatory Cytokine Secretion in Men with Overweight or Obesity: A 3-Period, Crossover, Randomized Controlled Trial.The Journal of nutrition · 2020Trial
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- Trial
- Defined Natural Products as Adjunctive Therapies: Evidence-Gated Polypharmacology Across Molecular Targets, Human Exposure, Clinical Signals, and Safety Boundaries.International journal of molecular sciences · 2026Review
- Rutin outperforms gallic acid in mitigating carbon tetrachloride-induced nephrotoxicity: Integrated in silico (docking, MD simulations, DFT) and in vivo mechanistic validation.Toxicology reports · 2026Article
- Evaluation of the antimicrobial potential of fluoride-free mouthwashes against Scardovia wiggsiae.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Comparative Molecular Docking and Pharmacokinetic Profiling of Cinnamic Acid and Oleic Acid fromInfectious disease reports · 2026Article
- Primary Metabolites in ThreeLife (Basel, Switzerland) · 2026Article
- HPTLC, GC-MS profiling, and biological activity comparison of Cinnamomum zeylanicum Blume (stem bark) essential oil between Indian and African varieties.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Multi-target antidiabetic and organ-protective effects of a polyherbal ethanol extract in STZ-induced diabetic rats.Frontiers in pharmacology · 2026Article
- The effect of cinnamon bark oil in bilateral common carotid artery occlusion-induced cerebral ıischemia model in rats.Scientific reports · 2025Article
- Antioxidant and Antiviral Potential of Cold-Brewed and Cold-Concentrated Plant Extracts.International journal of molecular sciences · 2025Article
- Bioactive Compounds and Traditional Uses ofMolecules (Basel, Switzerland) · 2025Article
- Comprehensive Phytochemical Analysis and Evaluation of Antioxidant, Antimicrobial, Cytotoxic, and Immunomodulatory Activities of Commercial Cinnamon Bark Essential Oil (International journal of molecular sciences · 2025Article
- Milpa Diet for MASLD in Mesoamerican Populations: Feasibility, Advantages, and Future Perspectives.Life (Basel, Switzerland) · 2025Review
- Enrichment of Oil Cake With Cinnamon Extract Positively Effects Antioxidant Activity and Textural Profile.Food science & nutrition · 2025Article
- Unraveling anthelmintic targets and mechanisms of action of trans-cinnamaldehyde from cinnamon essential oil.Scientific reports · 2025Article
- The effect ofJournal of medicine and life · 2025Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn traditional medicine Cinnamon is considered a remedy for respiratory, digestive and gynaecological ailments. In-vitro and in-vivo studies from different parts of the world have demonstrated numerous beneficial medicinal effects of Cinnamomum zeylanicum (CZ). This paper aims to systematically review the scientific literature and provide a comprehensive summary on the potential medicinal benefits of CZ.
methodsA comprehensive systematic review was conducted in the following databases; PubMed, Web of Science, SciVerse Scopus for studies published before 31st December 2012. The following keywords were used: "Cinnamomum zeylanicum", "Ceylon cinnamon", "True cinnamon" and "Sri Lankan cinnamon". To obtain additional data a manual search was performed using the reference lists of included articles.
resultsThe literature search identified the following number of articles in the respective databases; PubMed=54, Web of Science=76 and SciVerse Scopus=591. Thirteen additional articles were identified by searching reference lists. After removing duplicates the total number of articles included in the present review is 70. The beneficial health effects of CZ identified were; a) anti-microbial and anti-parasitic activity, b) lowering of blood glucose, blood pressure and serum cholesterol, c) anti-oxidant and free-radical scavenging properties, d) inhibition of tau aggregation and filament formation (hallmarks of Alzheimer's disease), e) inhibitory effects on osteoclastogenesis, f) anti-secretagogue and anti-gastric ulcer effects, g) anti-nociceptive and anti-inflammatory activity, h) wound healing properties and i) hepato-protective effects. The studies reported minimal toxic and adverse effects.
conclusionsThe available in-vitro and in-vivo evidence suggests that CZ has many beneficial health effects. However, since data on humans are sparse, randomized controlled trials in humans will be necessary to determine whether these effects have public health implications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.