Evidence map›Paper›PMID 24148866›Full record

ArticleGut pathogens2013

Gleaning evolutionary insights from the genome sequence of a probiotic yeast Saccharomyces boulardii.

Indu Khatri, Akil Akhtar, Kamaldeep Kaur, Rajul Tomar, Gandham Satyanarayana Prasad, Thirumalai Nallan Chakravarthy Ramya, Srikrishna Subramanian

Open access · goldAbstract read
In one paragraph

Article in Gut pathogens, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Genomic and phenotypic comparison ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Enhancing probiotic impact: engineeringApplied and environmental microbiology · 2024
    Article
  6. Article
  7. Article
  8. Journal of fungi (Basel, Switzerland) · 2020
    Review
  9. Article
  10. A Mutation inApplied and environmental microbiology · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Indu Khatri *CSIR-Institute of Microbial Technology, Chandigarh, India.
Akil Akhtar *CSIR-Institute of Microbial Technology, Chandigarh, India.
Kamaldeep KaurCSIR-Institute of Microbial Technology, Chandigarh, India.
Rajul TomarCSIR-Institute of Microbial Technology, Chandigarh, India.
Gandham Satyanarayana PrasadCSIR-Institute of Microbial Technology, Chandigarh, India.
Thirumalai Nallan Chakravarthy RamyaCSIR-Institute of Microbial Technology, Chandigarh, India.
Srikrishna SubramanianCSIR-Institute of Microbial Technology, Chandigarh, India.
Council of Scientific and Industrial Research · INInstitute of Microbial Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe yeast Saccharomyces boulardii is used worldwide as a probiotic to alleviate the effects of several gastrointestinal diseases and control antibiotics-associated diarrhea. While many studies report the probiotic effects of S. boulardii, no genome information for this yeast is currently available in the public domain.

resultsWe report the 11.4 Mbp draft genome of this probiotic yeast. The draft genome was obtained by assembling Roche 454 FLX + shotgun data into 194 contigs with an N50 of 251 Kbp. We compare our draft genome with all other Saccharomyces cerevisiae genomes.

conclusionsOur analysis confirms the close similarity of S. boulardii to S. cerevisiae strains and provides a framework to understand the probiotic effects of this yeast, which exhibits unique physiological and metabolic properties.

Identifiers

PMID24148866
PMCPMC3843575
OpenAlexW2104014973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.