Trial reportVaccine2013
A cluster randomised controlled trial of a web based decision aid to support parents' decisions about their child's Measles Mumps and Rubella (MMR) vaccination.
Trial report in Vaccine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024Pooled it
- Behavioral interventions for vaccination uptake: A systematic review and meta-analysis.Health policy (Amsterdam, Netherlands) · 2023Pooled it
- Interventions for COVID-19 Vaccine Hesitancy: A Systematic Review and Narrative Synthesis.International journal of environmental research and public health · 2023Pooled it
- Cost-Effectiveness Analyses of Digital Health Technology for Improving the Uptake of Vaccination Programs: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Vaccination in England: a review of why business as usual is not enough to maintain coverage.BMC public health · 2018Pooled it
- Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2017Pooled it
- Trial
- Japanese Encephalitis Vaccine Decision Aid for Travelers: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Addressing Parents' Vaccine Concerns: A Randomized Trial of a Social Media Intervention.American journal of preventive medicine · 2018Trial
- Effectiveness of a smartphone app to increase parents' knowledge and empowerment in the MMR vaccination decision: A randomized controlled trial.Human vaccines & immunotherapeutics · 2017Trial
- Text message reminders for timely routine MMR vaccination: A randomized controlled trial.Vaccine · 2015Trial
- Trial
- Cost effectiveness of a web-based decision aid for parents deciding about MMR vaccination: a three-arm cluster randomised controlled trial in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014Trial
- Mobile Vaccine Uptake (MoVeUP): a randomized effectiveness trial for a vaccine communication app.Vaccine: X · 2026Article
- Digital Gamification Tools to Enhance Vaccine Uptake: Scoping Review.JMIR serious games · 2024Article
- Decision aids to assist patients and professionals in choosing the right treatment for kidney failure.Clinical kidney journal · 2023Review
- Reducing COVID-19 Vaccine Decisional Conflict in Parents of 5-11-Year-Old Children in Australia: A Single Arm Pre-Post Study.Vaccines · 2023Article
- Article
- Using Behavioral Science to Address COVID-19 Vaccine Hesitancy Among Cancer Survivors: Communication Strategies and Research Opportunities.Journal of behavioral medicine · 2023Article
- Parental Decision Making Regarding COVID-19 Vaccines for Children under Age 5: Does Decision Self-Efficacy Play a Role?Vaccines · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectiveTo evaluate the effectiveness of a web based decision aid versus a leaflet versus, usual practice in reducing parents' decisional conflict for the first dose MMR vaccination decision. The, impact on MMR vaccine uptake was also explored.
designThree-arm cluster randomised controlled trial.
settingFifty GP practices in the north of, England.
participants220 first time parents making a first dose MMR decision.
interventionsWeb, based MMR decision aid plus usual practice, MMR leaflet plus usual practice versus usual practice only, (control).
main outcome measuresDecisional conflict was the primary outcome and used as the, measure of parents' levels of informed decision-making. MMR uptake was a secondary outcome.
resultsDecisional conflict decreased post-intervention for both intervention arms to a level where, parents could make an informed MMR decision (decision aid: effect estimate=1.09, 95% CI -1.36 to -0.82; information leaflet: effect estimate=-0.67, 95% CI -0.88 to -0.46). Trial arm was significantly, associated (p<0.001) with decisional conflict at post-intervention. Vaccination uptake was 100%, 91%, and 99% in the decision aid, leaflet and control arms, respectively (χ(2) (1, N=203)=8.69; p=0.017). Post-hoc tests revealed a statistically significant difference in uptake between the information leaflet, and the usual practice arms (p=0.04), and a near statistically significant difference between the, decision aid and leaflet arms (p=0.05).
conclusionsParents' decisional conflict was reduced in both, the decision aid and leaflet arms. The decision aid also prompted parents to act upon that decision and, vaccinate their child. Achieving both outcomes is fundamental to the integration of immunisation, decision aids within routine practice.
trial registrationISRCTN72521372.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.