ArticleJournal of the American Chemical Society2013
Facile and efficient preparation of anisotropic DNA-functionalized gold nanoparticles and their regioselective assembly.
Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Heterodimers of metal nanoparticles: synthesis, properties, and biological applications.Mikrochimica acta · 2021Review
- Light-Mediated Directed Placement of Different DNA Sequences on Single Gold Nanoparticles.Journal of the American Chemical Society · 2021Article
- Programming nanoparticle valence bonds with single-stranded DNA encoders.Nature materials · 2020Article
- Gold Nanorod Assemblies: The Roles of Hot-Spot Positioning and Anisotropy in Plasmon Coupling and SERS.Nanomaterials (Basel, Switzerland) · 2020Article
- Independent control over size, valence, and elemental composition in the synthesis of DNA-nanoparticle conjugates.Chemical science · 2020Article
- DNA-imprinted polymer nanoparticles with monodispersity and prescribed DNA-strand patterns.Nature chemistry · 2018Article
- Bottom-Up Strategy To Prepare Nanoparticles with a Single DNA Strand.Journal of the American Chemical Society · 2017Article
- Transfer of molecular recognition information from DNA nanostructures to gold nanoparticles.Nature chemistry · 2016Article
- DNA as a powerful tool for morphology control, spatial positioning, and dynamic assembly of nanoparticles.Accounts of chemical research · 2014Article
- Biomimetic RNA-silencing nanocomplexes: overcoming multidrug resistance in cancer cells.Angewandte Chemie (International ed. in English) · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Anisotropic nanoparticles can provide considerable opportunities for assembly of nanomaterials with unique structures and properties. However, most reported anisotropic nanoparticles are either difficult to prepare or to functionalize. Here we report a facile one-step solution-based method to prepare anisotropic DNA-functionalized gold nanoparticles (a-DNA-AuNP) with 96% yield and with high DNA density (120 ± 20 strands on the gold hemisphere). The method is based on the competition between a thiolated hydrophilic DNA and a thiolated hydrophobic phospholipid and has been applied to prepare a-DNA-AuNPs of different sizes and with a variety of DNA sequences. In addition, DNA strands on the a-DNA-AuNPs can be exchanged with other DNA strands with a different sequence. The anisotropic nature of the a-DNA-AuNPs allows regioselective hetero- and homonuclear assembly with high monodispersity, as well as regioselective functionalization of two different DNA strands for more diverse applications.
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