ReviewWorld journal of orthopedics2013
Normal and abnormal spine and thoracic cage development.
Review in World journal of orthopedics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.
- The use of magnetically controlled growing rod device for pediatric scoliosis.Neurosciences (Riyadh, Saudi Arabia) · 2016Pooled it
- A comparative study of strategies for spinal casting in early onset scoliosis : five-year progression-free survival analysis.Bone & joint open · 2026Article
- Effect of vosoritide on spine morphology in children with achondroplasia: 1-year results from a randomized phase 2 study.Journal of the Endocrine Society · 2026Article
- The Advanced Integrated Respiratory (AIR) Model: Integration of Air-Liquid Interface Cell Cultures within a Human Airway Model for Inhalation Toxicology.Pharmaceutical research · 2026Article
- Growth modulation and dynamic correction of early-onset thoracic scoliosis using a PEEK spring rib plate system: a porcine model study.Spine deformity · 2026Article
- Validation and Cultural Adaptation of the Polish Version of the 24-Item Early Onset Scoliosis Questionnaire (EOSQ-24).Journal of clinical medicine · 2025Article
- Development and Assessment of a Novel Generic Finite Element Spine Model for Clinical Applications.International journal for numerical methods in biomedical engineering · 2025Article
- Casting for early onset scoliosis in resource limited setting.International orthopaedics · 2025Article
- The risk factors for type ii respiratory failure in patients with severe scoliosis (less than 40-year old).Journal of orthopaedic surgery and research · 2025Article
- Review
- Perioperative complications after posterior spinal fusion versus minimally invasive fusionless surgery in neuromuscular scoliosis: a comparative study.Archives of orthopaedic and trauma surgery · 2023Article
- Nuances in Growing Rod Surgery: Our Initial Experience and Literature Review.Journal of orthopaedic case reports · 2023Article
- Effectiveness of the Boston Brace in the Treatment of Paediatric Scoliosis: A Longitudinal Study from 2010-2020 in a National Spinal Centre.Healthcare (Basel, Switzerland) · 2023Article
- Effects of spinal deformities on lung development in children: a review.Journal of orthopaedic surgery and research · 2023Review
- What to Expect of Feeding Abilities and Nutritional Aspects in Achondroplasia Patients: A Narrative Review.Genes · 2023Review
- Development of ribs and intercostal muscles in the chicken embryo.Journal of anatomy · 2022Article
- Early-onset scoliosis: a narrative review.EFORT open reviews · 2022Review
- Effects of Growing Rod Technique with Different Surgical Modes and Growth Phases on the Treatment Outcome of Early Onset Scoliosis: A 3-D Finite Element Analysis.International journal of environmental research and public health · 2022Article
- Spinal Cord Injury at Birth, Expected Medical and Health Complexity in Chronic Injury Guided Anew by Activity-Based Restorative Therapy: Case Report.Frontiers in psychology · 2022Article
- Vertebral body changes after continuous spinal distraction in scoliotic children.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Development of the spine and thoracic cage consists of a complex series of events involving multiple metabolic processes, genes and signaling pathways. During growth, complex phenomena occur in rapid succession. This succession of events, this establishment of elements, is programmed according to a hierarchy. These events are well synchronized to maintain harmonious limb, spine and thoracic cage relationships, as growth in the various body segments does not occur simultaneously at the same magnitude or rate. In most severe cases of untreated progressive early-onset spinal deformities, respiratory insufficiency and pulmonary and cardiac hypertension (cor pulmonale), which characterize thoracic insufficiency syndrome (TIS), can develop, sometimes leading to death. TIS is the inability of the thorax to ensure normal breathing. This clinical condition can be linked to costo-vertebral malformations (e.g., fused ribs, hemivertebrae, congenital bars), neuromuscular diseases (e.g., expiratory congenital hypotonia), Jeune or Jarcho-Levin syndromes or to 50% to 75% fusion of the thoracic spine before seven years of age. Complex spinal deformities alter normal growth plate development, and vertebral bodies become progressively distorted, perpetuating the disorder. Therefore, many scoliotic deformities can become growth plate disorders over time. This review aims to provide a comprehensive review of how spinal deformities can affect normal spine and thoracic cage growth. Previous conceptualizations are integrated with more recent scientific data to provide a better understanding of both normal and abnormal spine and thoracic cage growth.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.