Evidence map›Paper›PMID 24146877›Full record

SynthesisPloS one2013

Effects of high and low fat dairy food on cardio-metabolic risk factors: a meta-analysis of randomized studies.

Jocelyne R Benatar, Karishma Sidhu, Ralph A H Stewart

Expression of concernAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 72 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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  8. Effects of total fat intake on body fatness in adults.The Cochrane database of systematic reviews · 2020
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  13. Effects of total fat intake on bodyweight in children.The Cochrane database of systematic reviews · 2018
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  14. Effects of total fat intake on bodyweight in children.The Cochrane database of systematic reviews · 2018
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  16. Effects of total fat intake on body weight.The Cochrane database of systematic reviews · 2015
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jocelyne R BenatarGreen Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand.
Karishma Sidhu
Ralph A H Stewart

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceClear guidelines on the health effects of dairy food are important given the high prevalence of obesity, cardiovascular disease and diabetes, and increasing global consumption of dairy food.

objectiveTo evaluate the effects of increased dairy food on cardio metabolic risk factors. DATA SOURCES: Searches were performed until April 2013 using MEDLINE, Science Direct, Google,Embase, the Cochrane Central Register of Controlled Trials, reference lists of articles, and proceedings of major meetings. STUDY SELECTION: Randomized controlled studies with healthy adults randomized to increased dairy food for more than one month without additional interventions. DATA EXTRACTION AND SYNTHESIS: A standard list was used to extract descriptive, methodological and key variables from all eligible studies. If data was not included in the published report corresponding authors were contacted.

results20 studies with 1677 participants with a median duration of dietary change of 26 (IQR 10-39) weeks and mean increase in dairy food intake of 3.6 (SD 0.92) serves/day were included. Increased dairy food intake was associated with a modest weight gain (+0.59, 95% confidence interval 0.34 to 0.84kg, p<0.0001) but no significant change in waist circumference (0.35 , -0.75 to 1.45 cm); insulin resistance (HOMA –IR -0.94 , -1.93 to 0.05 units); fasting glucose (0.87, -0.27 to 2.01 mg/dl); LDL-cholesterol (1.36 ,-2.38 to 5.09 mg/dl); HDL-cholesterol (0.45, -2.13 to 3.04 mg/dl); systolic (-0.13, -1.73 to 1.98 mmHg) and diastolic blood pressure (0.13, -1.73 to 1.98 mmHg) or C-reactive protein (-0.08, -0.63 to 0.48 mg/L). Results were similar for studies with low-fat and whole-fat dairy interventions. LIMITATIONS: Most clinical trials were small and of modest quality. .

conclusionIncreasing whole fat and low fat dairy food consumption increases weight but has minor effects on other cardio-metabolic risk factors. TRIAL REGISTRATION ACTRN: Australian New Zealand Clinical Trials Registry ACTRN12613000401752, http://www.anzctr.org.au. ETHICS APPROVAL NUMBER: NTX/10/11/115.

Indexed as

Dairy ProductsAdultAgedBlood GlucoseBlood PressureBody WeightCardiovascular SystemCholesterol, HDLCholesterol, LDLC-Reactive ProteinDiastoleDietary FatsFastingFemaleHumansInsulin ResistanceBlood GlucoseCholesterol, HDLCholesterol, LDLC-Reactive ProteinDietary Fats

Identifiers

PMID24146877
PMCPMC3795726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.