ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2013
Evaluation of anti-bacterial and wound healing activity of the fruits of Amorpha fruticosa L.
Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of Topical Administration of Fractions and Isolated Molecules from Plant Extracts on Skin Wound Healing: A Systematic Review of Murine Experimental Models.Mediators of inflammation · 2016Pooled it
- Synergistic effects of herbal extracts and nanoparticles in skin damage repair: A comprehensive review.Avicenna journal of phytomedicine · 2026Review
- Analysis of bioactive constituents from the leaves of Amorpha fruticosa L.Journal of food and drug analysis · 2017Article
- Review
- Antibacterial constituents of Fructus Chebulae Immaturus and their mechanisms of action.BMC complementary and alternative medicine · 2016Article
- Toxicity of amorphigenin from the seeds of Amorpha fruticosa against the larvae of Culex pipiens pallens (Diptera: Culicidae).Molecules (Basel, Switzerland) · 2015Article
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Authors and funding
5 authors.
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Abstract
As the traditional Chinese medicine, the fresh fruits of Amorpha fruticosa L. were applied for the treatment of carbuncle, eczema and burn (Das et al., 2007). However, little is known about the functional roles of the fruits of Amorpha fruticosa L. during wound healing progress. In the present study, we evaluated both antimicrobial potential against a wide range of microorganisms and wound healing activity of the seven compounds isolated from the fruits of Amorpha fruticosa L in vitro and in vivo. Our results showed that compounds I (6a,12a-dehydroamorphin), V (dehydrosermundone) and VI (tephrosin) isolated from the fruits of Amorpha fruticosa L. performed dominant antimicrobial potential against microorganisms. Moreover, these compounds significantly enhanced fibroblasts proliferation and migration, leading to promotion of wound healing. Thus, it could be possible for the therapeutic utilization of Amorpha fruticosa L. for wound healing in the future.
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