Evidence map›Paper›PMID 24145854›Full record

ReviewImmunology and cell biology2014

Priming of T follicular helper cells by dendritic cells.

André Ballesteros-Tato, Troy D Randall

Abstract readReview
In one paragraph

Review in Immunology and cell biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Review
  2. Review
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  4. Article
  5. Review
  6. Article
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  8. Article
  9. Contribution of Dendritic Cell Subsets to T Cell-Dependent Responses in Mice.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  10. Strong influenza-induced TProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

André Ballesteros-TatoDivision of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Troy D RandallDivision of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

ROS Modulation of Innate and Adaptive Immunity in RAP30AR048311 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MOUNTZ, JOHN D · 2001 to 2017
$9.5M
Unique Aspects of Respiratory ImmunityR01HL069409 · NHLBI · UNIVERSITY OF ROCHESTER · PI RANDALL, TROY D · 2001 to 2015
$5.3M
Central and Effector B cells in the LungR01AI097357 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2012 to 2016
$1.8M
Generation of effective memory CD8 T cells to influenzaR01AI061511 · NIAID · UNIVERSITY OF ROCHESTER · PI RANDALL, TROY D · 2005 to 2009
$1.8M
Pulmonary Immunity To Pathogens In NeonatesR01AI100127 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2012 to 2016
$1.5M
NHLBI NIH HHS HL 069409NHLBI NIH HHS R01 HL069409NIAID NIH HHS AI 061511NIAID NIH HHS AI 097357NIAID NIH HHS AI100127NIAID NIH HHS R01 AI061511NIAID NIH HHS R01 AI097357NIAID NIH HHS R01 AI100127NIAMS NIH HHS AR 048311NIAMS NIH HHS P30 AR048311
6 · The paper itself

Abstract

T follicular helper cells (Tfh) are required to generate long-lived antibody responses, which confer long-term protection to pathogens following vaccination or infection. Despite significant advances in the field, however, little is known about the early steps that drive Tfh cell differentiation. In this review, we will discuss the mechanisms by which dendritic cells promote the initial commitment of activated CD4(+) T cells to the Tfh cell differentiation pathway.

Indexed as

Cell DifferentiationAnimalsDendritic CellsHumansT-Lymphocytes, Helper-Inducer

Identifiers

PMID24145854
PMCPMC4052723

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.