Evidence map›Paper›PMID 24145763›Full record

ArticleJournal of biomedical optics2013

Magnetomotive optical coherence elastography for microrheology of biological tissues.

Vasilica Crecea, Adeel Ahmad, Stephen A Boppart

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Life (Basel, Switzerland) · 2021
    Review
  3. Biomechanical sensing ofTheranostics · 2021
    Article
  4. Article
  5. Article
  6. Optical elastography and tissue biomechanics.Journal of biomedical optics · 2019
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vasilica CreceaUniversity of Illinois at Urbana-Champaign, Beckman Institute for Advanced Science and Technology, Urbana, Illinois 61801bUniversity of Illinois at Urbana-Champaign, Department of Physics, Urbana, Illinois 61801.
Adeel Ahmad
Stephen A Boppart

Funding

Targeted Microspheres for Contrast Enhancement in Optical Coherence TomographyR01EB009073 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2009 to 2012
$1.3M
NIBIB NIH HHS R01 EB009073
6 · The paper itself

Abstract

Optical coherence elastography (OCE) is an established paradigm for measuring biomechanical properties of tissues and cells noninvasively, in real time, and with high resolution. We present a different development of a spectral domain OCE technique that enables simultaneous measurements of multiple biomechanical parameters of biological tissues. Our approach extends the capabilities of magnetomotive OCE (MM-OCE), which utilizes iron oxide magnetic nanoparticles (MNPs) distributed and embedded in the specimens as transducers for inducing motion. Step-wise application of an external magnetic field results in displacements in the tissue specimens that are deduced from sensitive phase measurements made with the MM-OCE system. We analyzed freshly excised rabbit lung and muscle tissues. We observe that while they present some similarities, rabbit lung and muscle tissue displacements display characteristic differentiating features. Both tissue types undergo a fast initial displacement followed by a rapidly damped oscillation and the onset of creep. However, the damping is faster in muscle compared to lung tissue, while the creep is steeper in muscle. This approach has the potential to become a novel way of performing real-time measurements of biomechanical properties of tissues and to enable the development of different diagnostic and monitoring tools in biology and medicine.

Indexed as

AnimalsBiomechanical PhenomenaElasticity Imaging TechniquesLungMagnetite NanoparticlesMusclesRabbitsRheologyTomography, Optical CoherenceMagnetite Nanoparticles

Identifiers

PMID24145763
PMCPMC3800432

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.