Evidence map›Paper›PMID 24145697›Full record

ReviewMedicine2013

Fusarium infection: report of 26 cases and review of 97 cases from the literature.

Maged Muhammed, Theodora Anagnostou, Athanasios Desalermos, Themistoklis K Kourkoumpetis, Herman A Carneiro, Justin Glavis-Bloom, Jeffrey J Coleman, Eleftherios Mylonakis

Abstract readCase ReportsReview
In one paragraph

Review in Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Article
  2. Genome assembly of a clinicalMicrobiology resource announcements · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Non-JHLT open · 2025
    Review
  8. Clinical Features and Outcomes of InvasiveJournal of fungi (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Interaction Between Glycoside Hydrolase FsGH28c fromInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Journal of fungi (Basel, Switzerland) · 2024
    Article
  15. Rate, Risk Factors, and Outcomes of Invasive Fungal Infections in Patients with Hematologic Malignancies.International journal of hematology-oncology and stem cell research · 2024
    Article
  16. InvasiveFrontiers in medicine · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maged MuhammedFrom the Division of Infectious Diseases (MM, TA, AD, TKK, HAC, JG-B, JJC, EM), Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts; and Division of Infectious Diseases (TA, JJC, EM), Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.
Theodora Anagnostou
Athanasios Desalermos
Themistoklis K Kourkoumpetis
Herman A Carneiro
Justin Glavis-Bloom
Jeffrey J Coleman
Eleftherios Mylonakis

Funding

Technical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI Michael S Gilmore · 2009 to 2026
$39.4M
INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
A C.elegans high-throughput assay for the identification of new antifungal agentsR01AI075286 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MYLONAKIS, ELEFTHERIOS · 2008 to 2010
$1.3M
Genome-wide investigations in fungal pathogens utilizing an invertebrate model hoR21AI079569 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MYLONAKIS, ELEFTHERIOS · 2009 to 2010
$484k
NIAID NIH HHS AI075286NIAID NIH HHS AI079569NIAID NIH HHS P01 AI 083214NIAID NIH HHS P01 AI083214NIAID NIH HHS R01 AI075286NIAID NIH HHS R21 AI079569NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

Fusarium species is a ubiquitous fungus that causes opportunistic infections. We present 26 cases of invasive fusariosis categorized according to the European Organization for Research and Treatment of Cancer/Mycoses Study Group (EORTC/MSG) criteria of fungal infections. All cases (20 proven and 6 probable) were treated from January 2000 until January 2010. We also review 97 cases reported since 2000. The most important risk factors for invasive fusariosis in our patients were compromised immune system, specifically lung transplantation (n = 6) and hematologic malignancies (n = 5), and burns (n = 7 patients with skin fusariosis), while the most commonly infected site was the skin in 11 of 26 patients. The mortality rates among our patients with disseminated, skin, and pulmonary fusariosis were 50%, 40%, and 37.5%, respectively. Fusarium solani was the most frequent species, isolated from 49% of literature cases. Blood cultures were positive in 82% of both current study and literature patients with disseminated fusariosis, while the remaining 16% had 2 noncontiguous sites of infection but negative blood cultures. Surgical removal of focal lesions was effective in both current study and literature cases. Skin lesions in immunocompromised patients should raise the suspicion for skin or disseminated fusariosis. The combination of medical monotherapy with voriconazole or amphotericin B and surgery in such cases is highly suggested.

Indexed as

AdolescentAdultAgedChildChild, PreschoolDermatomycosesFemaleFusariosisFusariumHumansMaleMiddle AgedOpportunistic InfectionsRetrospective StudiesYoung Adult

Identifiers

PMID24145697
PMCPMC4553992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.