Evidence map›Paper›PMID 24145148›Full record

ReviewFrontiers in neuroendocrinology2014

Corticotropin releasing factor in neuroplasticity.

Limor Regev, Tallie Z Baram

Open access · greenAbstract readReview
In one paragraph

Review in Frontiers in neuroendocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Hearing and early life adversity: effects of developmental stress on sensory processing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  4. Article
  5. Article
  6. Article
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  9. Deficiency in the cell-adhesion moleculeFrontiers in cell and developmental biology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Revisiting the Stress Concept: Implications for Affective Disorders.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Limor RegevDepartments of Anatomy/Neurobiology, University of California-Irvine, Irvine, CA, USA.
Tallie Z BaramDepartments of Anatomy/Neurobiology, University of California-Irvine, Irvine, CA, USA; Department of Pediatrics, University of California-Irvine, Irvine, CA, USA. Electronic address: tallie@uci.edu.
University of California, Irvine · US

Funding

Structural & Network-Function Correlates of Fragmented Early-Life Across SpeciesP50MH096889 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 2013 to 2023
$25.4M
The Spine Cytoskeleton and Memory DisordersP01NS045260 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 2003 to 2015
$14.4M
Effects of Early-Life Experience: Role of CRHR01MH073136 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 2005 to 2020
$4.6M
CRH-MRNA REGULATION--ROLE IN NEONATAL SEIZURE POTENTIALR01NS028912 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 1992 to 2014
$4.2M
NIMH NIH HHS MH73136NIMH NIH HHS P50 MH096889NIMH NIH HHS R01 MH073136NINDS NIH HHS NS28912NINDS NIH HHS NS45260NINDS NIH HHS P01 NS045260NINDS NIH HHS R01 NS028912
6 · The paper itself

Abstract

Stress is among the strongest signals promoting neuroplasticity: Stress signals, indicating real or perceived danger, lead to alterations of neuronal function and often structure, designed to adapt to the changed conditions and promote survival. Corticotropin releasing factor (CRF) is expressed and released in several types of neuronal populations that are involved in cognition, emotion and the regulation of autonomic and endocrine function. CRF expressing neurons undergo functional and structural plasticity during stress and, in addition, the peptide acts via specific receptors to promote plasticity of target neurons.

Indexed as

AnimalsCorticotropin-Releasing HormoneHumansMemoryNeuronal PlasticityNeuronsStress, PhysiologicalCorticotropin-Releasing HormoneCRFEpigeneticsHippocampusHypothalamusMemoryNeuropeptidePlasticityStressSynapse

Identifiers

PMID24145148
PMCPMC3965598
OpenAlexW2036141691

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.