Evidence map›Paper›PMID 24145142›Full record

ArticleJournal of proteomics2014

The strategy, organization, and progress of the HUPO Human Proteome Project.

Gilbert S Omenn

Abstract read
In one paragraph

Article in Journal of proteomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. 'Omics Approaches to Explore the Breast Cancer Landscape.Frontiers in cell and developmental biology · 2019
    Review
  5. Article
  6. Article
  7. Shared resources, shared costs--leveraging biocuration resources.Database : the journal of biological databases and curation · 2015
    Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gilbert S OmennCenter for Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI 48109-2218, USA. Electronic address: gomenn@umich.edu.

Funding

MICHIGAN INSTITUTE FOR CLINICAL AND HEALTH RESEARCH (MICHR) (UL1): (BPCA)UL1RR024986 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2007 to 2011
$51.2M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Replication of Human Endogenous Retroviruses in Modern HumansR01CA144043 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARKOVITZ, DAVID MICHAEL · 2009 to 2013
$6.4M
NCI NIH HHS R01 CA144043NCRR NIH HHS UL1 RR024986NIEHS NIH HHS P30 ES017885
6 · The paper itself

Abstract

The Human Proteome Project is a major, comprehensive initiative of the Human Proteome Organization. This global collaborative effort aims to identify and characterize at least one protein product and many PTM, SAP, and splice variant isoforms from the 20,300 human protein-coding genes. The deliverables are an extensive parts list and an array of technology platforms, reagents, spectral libraries, and linked knowledge bases that advance the field and facilitate the use of proteomics by a much wider community of life scientists. Such enablement will help address the Grand Challenge of using proteomics to bridge major gaps between evidence of genomic variation and diverse phenotypes. BIOLOGICAL SIGNIFICANCE: The HUPO Human Proteome Project (HPP) has made an outstanding launch, including a special issue of the Journal of Proteome Research on the Chromosome-centric HPP with a total of 48 articles. This article is part of a Special Issue: Can Proteomics Fill the Gap Between Genomics and Phenotypes?

Indexed as

Databases, ProteinInternational CooperationAlternative SplicingChromosomes, HumanHuman Genome ProjectHumansKnowledge BasesPolymorphism, GeneticProtein IsoformsProtein Processing, Post-TranslationalProteomeProteomicsProtein IsoformsProteomeBiology and Disease-driven Human Proteome ProjectChromosome-centric Human Proteome ProjectHUPO Human Proteome ProjectMissing proteinsPeptideAtlasProteomeXchange

Identifiers

PMID24145142
PMCPMC3972288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.