SynthesisGeneral hospital psychiatry
The prevalence of bipolar disorder in general primary care samples: a systematic review.
Synthesis in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of the literature on telepsychiatry for bipolar disorder.Brain and behavior · 2022Pooled it
- Lifestyle interventions targeting dietary habits and exercise in bipolar disorder: A systematic review.Journal of psychiatric research · 2016Pooled it
- Clinical Predictors of Engagement in Teleintegrated Care and Telereferral Care for Complex Psychiatric Disorders in Primary Care: a Randomized Trial.Journal of general internal medicine · 2022Trial
- A randomized pilot study of Rhythms And You (RAY): An internet-based program for bipolar disorder administered with and without clinical helper support in primary care.Journal of affective disorders · 2021Trial
- Article
- HIV Diagnosis and Preexposure Prophylaxis (PrEP) Prescription Among Commercially Insured Persons With Bipolar Disorder.The Journal of clinical psychiatry · 2025Article
- The Inaccuracy of the Mood Disorder Questionnaire for Bipolar Disorder in a Community Sample: From the "DYMERS" Construct Toward a New Instrument for Detecting Vulnerable Conditions.Journal of clinical medicine · 2025Article
- Risk of periodontitis in adolescents with bipolar disorder: a cohort study of 21,255 subjects.European child & adolescent psychiatry · 2024Article
- Pediatric Medical Traumatic Stress (PMTS) following Surgery in Childhood and Adolescence: a Systematic Review.Journal of child & adolescent trauma · 2022Article
- Treating Bipolar Disorder in Primary Care: Diagnosis, Pharmacology, and Management.International journal of general medicine · 2022Article
- Symptom continuum reported by affective disorder patients through a structure-validated questionnaire.BMC psychiatry · 2020Article
- Mental health in UK Biobank - development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis.BJPsych open · 2020Article
- Bipolar disorder in primary care: a qualitative study of clinician and patient experiences with diagnosis and treatment.Family practice · 2019Article
- Experiences of Mental Healthcare Reported by Individuals Diagnosed with Bipolar Disorder: An Italian Qualitative Study.Community mental health journal · 2019Article
- High Frequency of Bipolar Disorder Comorbidity in Medical Inpatients.Iranian journal of psychiatry · 2019Article
- Implementation of evidence-based practices for complex mood disorders in primary care safety net clinics.Families, systems & health : the journal of collaborative family healthcare · 2018Article
- Estimating the Prevalence of Serious Mental Illness and Dementia Diagnoses Among Medicare Beneficiaries in the Health and Retirement Study.Research on aging · 2018Article
- Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants.BJPsych open · 2018Article
- Article
- Bipolar disorder and adherence: implications of manic subjective experience on treatment disruption.Patient preference and adherence · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveTo obtain an estimate of the prevalence of bipolar disorder in primary care.
methodsWe used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method to conduct a systematic review in January 2013. We searched seven databases with a comprehensive list of search terms. Included articles had a sample size of 200 patients or more and assessed bipolar disorder using a structured clinical interview or bipolar screening questionnaire in random adult primary care patients. Risk of bias in each study was also assessed.
resultsWe found 5595 unique records in our search. Fifteen studies met our inclusion criteria. The percentage of patients with bipolar disorder found on structured psychiatric interviews in 10 of 12 studies ranged from 0.5% to 4.3%, and a positive screen for bipolar disorder using a bipolar disorder questionnaire was found in 7.6% to 9.8% of patients.
conclusionIn 10 of 12 studies using a structured psychiatric interview, approximately 0.5% to 4.3% of primary care patients were found to have bipolar disorder, with as many as 9.3% having bipolar spectrum illness in some settings. Prevalence estimates from studies using screening measures that have been found to have low positive predictive value were generally higher than those found using structured interviews.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.