ArticleAsian Pacific journal of tropical biomedicine2014
Serum uric acid level in newly diagnosed essential hypertension in a Nepalese population: a hospital based cross sectional study.
Article in Asian Pacific journal of tropical biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 32 citations in OpenAlex.
- Hyperuricemia and associated factors among hypertensive patients attending an academic hospital of Ethiopia: A cross-sectional study.Metabolism open · 2024Article
- Exploring the Effects of Elevated Serum Uric Acid Levels on Hypertension: A Scoping Review of Hyperuricemia.Cureus · 2023Article
- Serum uric acid and left ventricular hypertrophy in hypertensive patients in Ado-Ekiti.The Pan African medical journal · 2020Article
- Role of Dietary Components in Modulating Hypertension.Journal of clinical & experimental cardiology · 2016Article
- Hyperuricaemia - A Potential Indicator to Diagnose the Risk of Essential Hypertension.Journal of clinical and diagnostic research : JCDR · 2016Article
- Serum uric acid and target organ damage in essential hypertension.Vascular health and risk management · 2014Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo develop the missing link between hyperuricemia and hypertension.
methodsThe study was conducted in Department of Biochemistry in collaboration with Nephrology Unit of Internal Medicine Department. Hypertension was defined according to blood pressure readings by definitions of the Seventh Report of the Joint National Committee. Totally 205 newly diagnosed and untreated essential hypertensive cases and age-sex matched normotensive controls were enrolled in the study. The potential confounding factors of hyperuricemia and hypertension in both cases and controls were controlled. Uric acid levels in all participants were analyzed.
resultsRenal function between newly diagnosed hypertensive cases and normotensive healthy controls were adjusted. The mean serum uric acid observed in newly diagnosed hypertensive cases and in normotensive healthy controls were (290.05±87.05) μmol/L and (245.24±99.38) μmol/L respectively. A total of 59 (28.8%) participants of cases and 28 (13.7%) participants of controls had hyperuricemia (odds ratio 2.555 (95% CI: 1.549-4.213), P<0.001).
conclusionsThe mean serum uric acid levels and number of hyperuricemic subjects were found to be significantly higher in cases when compared to controls.
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