ArticleInorganic chemistry2014
Metabolic tumor profiling with pH, oxygen, and glucose chemosensors on a quantum dot scaffold.
Article in Inorganic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Designer Heme Proteins: Achieving Novel Function with Abiological Heme Analogues.Accounts of chemical research · 2021Article
- Corrole-Substituted Fluorescent Heme Proteins.Inorganic chemistry · 2021Article
- Imaging the Tumor Microenvironment.Advances in experimental medicine and biology · 2017Review
- Ratiometric QD-FRET Sensing of Aqueous H2S in Vitro.Analytical chemistry · 2016Article
- Advancing biomedical imaging.Proceedings of the National Academy of Sciences of the United States of America · 2015Review
- A Barcoding Strategy Enabling Higher-Throughput Library Screening by Microscopy.ACS synthetic biology · 2015Article
- A methacrylate-based polymeric imidazole ligand yields quantum dots with low cytotoxicity and low nonspecific binding.Journal of colloid and interface science · 2015Article
- Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors.Journal of the American Chemical Society · 2015Article
- Pyrene-Capped CdSe@ZnS Nanoparticles as Sensitive Flexible Oxygen Sensors in Non-Aqueous Media.ChemistryOpen · 2014Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Acidity, hypoxia, and glucose levels characterize the tumor microenvironment rendering pH, pO2, and pGlucose, respectively, important indicators of tumor health. To this end, understanding how these parameters change can be a powerful tool for the development of novel and effective therapeutics. We have designed optical chemosensors that feature a quantum dot and an analyte-responsive dye. These noninvasive chemosensors permit pH, oxygen, and glucose to be monitored dynamically within the tumor microenvironment by using multiphoton imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.