ArticleThe Plant cell2013
Laccase is necessary and nonredundant with peroxidase for lignin polymerization during vascular development in Arabidopsis.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 278 papers.
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Who cites it
278 citing papers in PubMed, 601 citations in OpenAlex.
- Multimodal Analysis and Heterologous Expression Strategies Reveal the Crucial Role of the Lac2 Gene fromJournal of fungi (Basel, Switzerland) · 2026Article
- The Plant Cell Wall: From Structural Diversity and Biosynthesis to Integrity Signaling and Physiological Functions.Plants (Basel, Switzerland) · 2026Review
- The Dual Role of Lignin in Fruit Trees: Unraveling Regulatory Networks from Stress Resilience to Quality Control.Plants (Basel, Switzerland) · 2026Review
- Functional Analysis of the GH16 Domain-ContainingPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Identification, Expression Profiling, and microRNA397-Mediated Regulation of Laccase Genes inPlants (Basel, Switzerland) · 2026Article
- Marker-trait associations and superior haplotypes for rice straw cell wall components and their relationship with digestibility and agronomic traits.BMC plant biology · 2026Article
- Conserved 4-coumarate 3-hydroxylase/ascorbate peroxidase bifunctionality coordinates lignin deposition and plant growth in Brachypodium and Populus.Plant physiology · 2026Article
- Reducing nitrogen with dense planting increase sweetpotato storage roots quantity via favoring starch synthesis over lignification.iScience · 2026Article
- Parasitic Plant-Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Genome-wide association and haplotype analyses reveal genetic architecture of seed dormancy in grain sorghum with implications for preharvest sprouting tolerance.The plant genome · 2026Article
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- Transcriptional Modulation in Grapevine by a Biostimulant Treatment for Improved Plant Resilience to Stress Events.Plants (Basel, Switzerland) · 2026Article
- Regulatory Roles of MYB Transcription Factors in Root Barrier Under Abiotic Stress.Plants (Basel, Switzerland) · 2026Review
- The LoMYB26/LoJAZ4-LoCOMT module regulates anther dehiscence via Jasmonic acid-mediated endothecium lignification in lily.Journal of advanced research · 2026Article
- Integrated transcriptomic and metabolomic analysis of provenances and organ-specific responses to drought and rehydration inFrontiers in plant science · 2026Article
- A functional PCR-CTPP marker targeting an intronic SNP inFrontiers in plant science · 2026Article
- A high spatial resolution transcriptomics of tension wood reveals the genetic program of contractile G-layer formation.Frontiers in plant science · 2026Article
- Exploring the molecular landscape of environmental responses in the Antarctic plantFrontiers in plant science · 2026Article
- Using transcriptome analysis and QTL mapping to decipher the genetic basis of heterosis in potato root system.BMC plant biology · 2025Article
218 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evolution of lignin biosynthesis was critical in the transition of plants from an aquatic to an upright terrestrial lifestyle. Lignin is assembled by oxidative polymerization of two major monomers, coniferyl alcohol and sinapyl alcohol. Although two recently discovered laccases, LAC4 and LAC17, have been shown to play a role in lignin polymerization in Arabidopsis thaliana, disruption of both genes only leads to a relatively small change in lignin content and only under continuous illumination. Simultaneous disruption of LAC11 along with LAC4 and LAC17 causes severe plant growth arrest, narrower root diameter, indehiscent anthers, and vascular development arrest with lack of lignification. Genome-wide transcript analysis revealed that all the putative lignin peroxidase genes are expressed at normal levels or even higher in the laccase triple mutant, suggesting that lignin laccase activity is necessary and nonredundant with peroxidase activity for monolignol polymerization during plant vascular development. Interestingly, even though lignin deposition in roots is almost completely abolished in the lac11 lac4 lac17 triple mutant, the Casparian strip, which is lignified through the activity of peroxidase, is still functional. Phylogenetic analysis revealed that lignin laccase genes have no orthologs in lower plant species, suggesting that the monolignol laccase genes diverged after the evolution of seed plants.
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