Evidence map›Paper›PMID 24142422›Full record

ArticleObesity surgery2014

Favorable changes in arterial elasticity, left ventricular mass, and diastolic function after significant weight loss following laparoscopic sleeve gastrectomy in obese individuals.

Mădălina E Iancu, Cătălin Copăescu, Marinela Şerban, Carmen Ginghină

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Article in Obesity surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

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17citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Bariatric surgery as a treatment for heart failure: review of the literature and potential mechanisms.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2018
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Mădălina E IancuBariatric and Metabolic Surgery Centre of Excellence, Ponderas Hospital, Str. Rãcari, nr. 6A, sector 3, Bucharest, Romania, madalina.iancu@gmail.com.
Cătălin Copăescu
Marinela Şerban
Carmen Ginghină

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is accompanied by increased arterial stiffness, left ventricular (LV) hypertrophy, and diastolic dysfunction, all associated with a negative prognosis. The evolution of LV mass, function, and arterial elasticity after laparoscopic sleeve gastrectomy (LSG) was unknown, and this is what we have investigated.

methodsThirty-four consecutive obese subjects (mean age, 39 ± 11 years; 35.2 % men), scheduled for LSG, were studied before, at 6 and 12 months after surgery.

resultsThe body mass index (BMI) decreased from 43.6 ± 11.9 to 32.1 ± 7.4 and to 28.9 ± 5.8 kg/m(2) at 6 and 12 months after surgery (all p < 0.05). The baseline LV mass index was correlated with age, BMI, waist circumference, blood glucose level, systemic hypertension stage, and with aortic distensibility, strain, and stiffness index (all p < 0.05). Aortic distensibility increased by 110 %, aortic strain by 58 %, and aortic stiffness index decreased by 88 % at 6 months after LSG (all p(6 months-baseline) < 0.05) and all the parameters had similar values at 12 months postoperatively (all p(12-6 months) = NS). LV hypertrophy prevalence decreased from 61.8 to 47.1 % and to 32.3 % at 6 and 12 months after surgery (all p < 0.05). The proportion of patients with LV diastolic dysfunction decreased from 52.9 to 23.5 % at 6 months (p(6 months-baseline) < 0.01) and to 20.6 % at 12 months postoperatively (p(12 -6 months)= 0.7).

conclusionsSignificant improvements of aortic elasticity and of LV diastolic function were recorded at 6 months, and they were maintained at 12 months after LSG. The LV hypertrophy showed also a favorable evolution: it has been slightly improved 6 months after surgery and further ameliorated 1 year postoperatively.

Indexed as

EchocardiographyGastrectomyLaparoscopyWeight LossAdultAortic DiseasesBlood PressureBody Mass IndexElasticityFemaleFollow-Up StudiesHumansMaleObesity, MorbidPostoperative PeriodProspective Studies

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.