ArticleMolecular medicine reports2013
ADAM33 polymorphisms are associated with asthma and a distinctive palm dermatoglyphic pattern.
Article in Molecular medicine reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Association between ADAM33 polymorphisms and asthma risk: a systematic review and meta-analysis.Respiratory research · 2019Pooled it
- Assessment of Environmental and Hereditary Influence on Development of Pituitary Tumors Using Dermatoglyphic Traits and Their Potential as Screening Markers.International journal of environmental research and public health · 2016Trial
- Role of theInternational journal of molecular sciences · 2025Article
- Dermatoglyphic pattern, an anatomical indicator of bronchial asthma: A case control study.Bioinformation · 2025Article
- ADAM33's Role in Asthma Pathogenesis: An Overview.International journal of molecular sciences · 2024Review
- Association betweenDiagnostics (Basel, Switzerland) · 2023Article
- Genetic association of ADAM33 polymorphisms with childhood asthma in Chinese Han population: A case-control study.Medicine · 2019Observational
- Article
- Palm dermatoglyphs and interleukin-4 receptor polymorphisms in asthma.Biomedical reports · 2017Article
- Association study on ADAM33 polymorphisms in mite-sensitized persistent allergic rhinitis in a Chinese population.PloS one · 2014Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A close correlation between asthma and palm dermatoglyphic patterns has been observed in previous studies, but the underlying genetic mechanisms have not been investigated. A disintegrin and metalloprotein‑33 (ADAM33) polymorphisms are important in the development of asthma and other atopic diseases. To investigate the underlying mechanisms of the association between asthma and distinctive palm dermatoglyphic patterns, thirteen ADAM33 single‑nucleotide polymorphisms (SNPs) were analyzed for the association between asthma and palm dermatoglyphic patterns in a population of 400 asthmatic patients and 200 healthy controls. Based on the results, five SNPs, rs44707 (codominant model, P=0.031; log‑additive model, P=0.0084), rs2787094 (overdominant model, P=0.049), rs678881 (codominant model, P=0.028; overdominant model, P=0.0083), rs677044 (codominant model, P=0.013; log‑additive model, P=0.0033) and rs512625 (dominant model, P=0.033), were associated with asthma in this population. Two SNPs, rs44707 (dominant model, P=0.042) and rs2787094 (codominant model, P=0.014; recessive model, P=0.0038), were observed in the asthma patients with the distinctive palm pattern. As rs44707 and rs2787094 are associated with asthma and a distinctive palm pattern, the data suggest that ADAM33 polymorphisms are correlated with asthma and may be the underlying genetic basis of the association between asthma and palm dermatoglyphic patterns.
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