ArticleChemical communications (Cambridge, England)2014
New cross-bridged cyclam derivative CB-TE1K1P, an improved bifunctional chelator for copper radionuclides.
Article in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- [ACS omega · 2026Article
- Molecular targets and the emerging role of copper radionuclides in prostate cancer theranostics.EJNMMI research · 2025Review
- Zirconium 89 and Copper 64 for ImmunoPET: From Antibody Bioconjugation and Radiolabeling to Molecular Imaging.Pharmaceutics · 2024Review
- Endeavor toward Redox-Responsive Transition Metal Contrast Agents Based on the Cross-Bridge Cyclam Platform.Inorganic chemistry · 2024Article
- Recent progress in the imaging of c-Met aberrant cancers with positron emission tomography.Medicinal research reviews · 2022Review
- Recent Advances in Bioorthogonal Click Chemistry for Efficient Synthesis of Radiotracers and Radiopharmaceuticals.Molecules (Basel, Switzerland) · 2019Review
- Article
- Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.Nature chemical biology · 2019Article
- Article
- Metal-Based PSMA Radioligands.Molecules (Basel, Switzerland) · 2017Review
- Aspartate-Based CXCR4 Chemokine Receptor Binding of Cross-Bridged Tetraazamacrocyclic Copper(II) and Zinc(II) Complexes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2016Article
- New Bifunctional Chelator p-SCN-PhPr-NE3TA for Copper-64: Synthesis, Peptidomimetic Conjugation, Radiolabeling, and Evaluation for PET Imaging.Inorganic chemistry · 2016Article
- Targeting PSMA with a Cu-64 Labeled Phosphoramidate Inhibitor for PET/CT Imaging of Variant PSMA-Expressing Xenografts in Mouse Models of Prostate Cancer.Molecular imaging and biology · 2016Article
- Universal Molecular Scaffold for Facile Construction of Multivalent and Multimodal Imaging Probes.Bioconjugate chemistry · 2016Article
- Highly-efficient and versatile fluorous-tagged Cu(I)-catalyzed azide-alkyne cycloaddition ligand for preparing bioconjugates.Chemical communications (Cambridge, England) · 2015Article
- Click-chemistry strategy for labeling antibodies with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold.Bioconjugate chemistry · 2015Article
- Comparison of conjugation strategies of cross-bridged macrocyclic chelators with cetuximab for copper-64 radiolabeling and PET imaging of EGFR in colorectal tumor-bearing mice.Molecular pharmaceutics · 2014Article
- 64Cu-labeled somatostatin analogues conjugated with cross-bridged phosphonate-based chelators via strain-promoted click chemistry for PET imaging: in silico through in vivo studies.Journal of medicinal chemistry · 2014Article
- Radioimmunoimaging of liver metastases with PET using a 64Cu-labeled CEA antibody in transgenic mice.PloS one · 2014Article
- Drug delivery systems, CNS protection, and the blood brain barrier.BioMed research international · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
A new cross-bridged cyclam chelator, CB-TE1K1P, was developed for copper-based radiopharmaceuticals, and this chelator can be labelled with (64)Cu under mild conditions in high specific activity. DBCO-PEG4-CB-TE1K1P was synthesized for conjugation to proteins, while Dde-CB-TE1K1P((t)Bu2)-OH was synthesized for solid-phase peptide synthesis. Examples of the conjugation chemistry, radiolabelling and serum stability of each are presented.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.