ArticleNature neuroscience2013
Common medial frontal mechanisms of adaptive control in humans and rodents.
Article in Nature neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 4 of them syntheses that pooled it.
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Who cites it
148 citing papers in PubMed, 4 syntheses or guidelines pooled it, 284 citations in OpenAlex.
- Consistent neural evidence to support novelty and appropriateness processing for creative thinking: a coordinated meta-analysis using activation likelihood estimation.Brain structure & function · 2026Pooled it
- Success versus failure in cognitive control: Meta-analytic evidence from neuroimaging studies on error processing.Neuroscience and biobehavioral reviews · 2024Pooled it
- Meta-analysis of aberrant post-error slowing in substance use disorder: implications for behavioral adaptation and self-control.The European journal of neuroscience · 2019Pooled it
- Frontal midline theta reflects anxiety and cognitive control: meta-analytic evidence.Journal of physiology, ParisPooled it
- Family-based care buffers the stress sensitizing effect of early deprivation on executive functioning difficulties in adolescence.Child development · 2023Trial
- Adolescent cognitive control and mediofrontal theta oscillations are disrupted by neglect: Associations with transdiagnostic risk for psychopathology in a randomized controlled trial.Developmental cognitive neuroscience · 2020Trial
- An evolutionary conserved neural mechanism for interpersonal coordination in primates.Science advances · 2026Article
- Understanding human metacontrol and its pathologies using deep neural networks.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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- A shared ensemble in the prelimbic cortex links impulsivity and anxiety-like behavior.bioRxiv : the preprint server for biology · 2025Article
- Attention- and action-related oscillatory dynamics in a visuomotor network.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Prefrontal Network Mechanisms of Psychiatric Deep Brain Stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Amphetamine increases timing variability by degrading prefrontal temporal encoding.Neuropharmacology · 2025Article
- Electrophysiological correlates of inhibitory control in children: Relations with prenatal maternal risk factors and child psychopathology.Development and psychopathology · 2025Article
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- Theta and beta power in the subthalamic nucleus responds to conflict across subregions and hemispheres.Brain communications · 2025Article
- Emotion regulation strategies explain associations of theta and Beta with positive affect.Psychophysiology · 2025Article
- Sensation seeking and risk adjustment: the role of reward sensitivity in dynamic risky decisions.Frontiers in behavioral neuroscience · 2025Article
- Disruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder.Nature medicine · 2024Article
88 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
In this report we describe how common brain networks within the medial frontal cortex (MFC) facilitate adaptive behavioral control in rodents and humans. We demonstrate that after errors, low-frequency oscillations below 12 Hz are modulated over the midfrontal cortex in humans and within the prelimbic and anterior cingulate regions of the MFC in rats. These oscillations were phase locked between the MFC and motor areas in both rats and humans. In rats, single neurons that encoded prior behavioral outcomes were phase coherent with low-frequency field oscillations, particularly after errors. Inactivating the medial frontal regions in rats led to impaired behavioral adjustments after errors, eliminated the differential expression of low-frequency oscillations after errors and increased low-frequency spike-field coupling within the motor cortex. Our results describe a new mechanism for behavioral adaptation through low-frequency oscillations and elucidate how medial frontal networks synchronize brain activity to guide performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.