Evidence map›Paper›PMID 24141087›Full record

ReviewMicrobes and infection2013

Ehrlichia moonlighting effectors and interkingdom interactions with the mononuclear phagocyte.

Paige Selvy Dunphy, Tian Luo, Jere W McBride

Abstract readReview
In one paragraph

Review in Microbes and infection, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Antibody reactive immunomes ofFrontiers in cellular and infection microbiology · 2023
    Article
  2. mBio · 2022
    Article
  3. Moonlighting in Rickettsiales: Expanding Virulence Landscape.Tropical medicine and infectious disease · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Frontiers in immunology · 2021
    Review
  8. Review
  9. Discovery ofFrontiers in cellular and infection microbiology · 2020
    Article
  10. NPJ vaccines · 2020
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Paige Selvy DunphyDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA.
Tian Luo
Jere W McBride
The University of Texas Medical Branch at Galveston · US

Funding

Training in Emerging Infectious Diseases and BiodefenseT32AI007536 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI WHITE, ARTHUR CLINTON · 1998 to 2013
$4.1M
Ehrlichia Type-1 Secreted Effectors Exploit Host SUMO PathwaysR21AI105536 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MCBRIDE, JERE W · 2013 to 2014
$421k
NIAID NIH HHS AI105536NIAID NIH HHS R21 AI105536NIAID NIH HHS T32 AI007536
6 · The paper itself

Abstract

Ehrlichia chaffeensis is an obligately intracellular gram negative bacterium with a small genome that thrives in mammalian mononuclear phagocytes by exploiting eukaryotic processes. Herein, we discuss the latest findings on moonlighting tandem repeat protein effectors and their secretion mechanisms, and novel molecular interkingdom interactions that provide insight into the intracellular pathobiology of ehrlichiae.

Indexed as

Host-Pathogen InteractionsAnimalsAnkyrinsBacterial ProteinsBacterial Secretion SystemsCell NucleusEhrlichiaEhrlichiosisGene Expression Regulation, BacterialGenome, BacterialHumansIntracellular SpacePhagocytesProtein BindingProtein TransportTransient Receptor Potential ChannelsAnkyrinsBacterial ProteinsBacterial Secretion SystemsTransient Receptor Potential ChannelsEffectorEhrlichiaHuman monocytotropic ehrlichiosisMoonlighting proteinNucleomodulinPost translational modificationTandem repeat proteinType 1 secretion systemZoonosis

Identifiers

PMID24141087
PMCPMC3886233
OpenAlexW2081112859

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.