ArticleThe Journal of allergy and clinical immunology2014
Prematurity, atopy, and childhood asthma in Puerto Ricans.
Article in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth.Epigenetics · 2021Pooled it
- Article
- Exposure to violence and asthma in Puerto Rican youth with high Th2 immunity.Pediatric pulmonology · 2023Article
- Characteristics of inpatients with atopic asthma in a tertiary center: do age and gender have an influence?Multidisciplinary respiratory medicine · 2022Article
- Association between factors related to the pregnancy, neonatal period, and later complications (especially asthma) and menarcheal age in a sample of Lebanese girls.BMC women's health · 2020Article
- Risk factors for atopic and nonatopic asthma in Puerto Rican children.Pediatric pulmonology · 2020Article
- Cohort profile: Center for Research on Early Childhood Exposure and Development in Puerto Rico.BMJ open · 2020Article
- Respiratory morbidity, atopy and asthma at school age in preterm infants aged 32-35 weeks.European journal of pediatrics · 2019Observational
- Social, Environmental and Behavioral Determinants of Asthma Symptoms in Brazilian Middle School Students-A National School Health Survey (Pense 2012).International journal of environmental research and public health · 2018Article
- Does the sex of the preterm baby affect respiratory outcomes?Breathe (Sheffield, England) · 2018Review
- Prenatal, intrapartum, and postnatal factors are associated with pediatric eosinophilic esophagitis.The Journal of allergy and clinical immunology · 2018Article
- Cockroach allergen exposure and plasma cytokines among children in a tropical environment.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017Article
- Maternal depressive symptoms, maternal asthma, and asthma in school-aged children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017Article
- Preterm Birth Affects the Risk of Developing Immune-Mediated Diseases.Frontiers in immunology · 2017Article
- Proximity to a Major Road and Plasma Cytokines in School-Aged Children.Pediatric allergy, immunology, and pulmonology · 2016Article
- Gun Violence, African Ancestry, and Asthma: A Case-Control Study in Puerto Rican Children.Chest · 2016Article
- Assessing Early Life Factors for Eosinophilic Esophagitis: Lessons From Other Allergic Diseases.Current treatment options in gastroenterology · 2016Article
- Pulmonary Disease and Age at Immigration among Hispanics. Results from the Hispanic Community Health Study/Study of Latinos.American journal of respiratory and critical care medicine · 2016Article
- Article
- Prenatal Stress, Prematurity, and Asthma.Obstetrical & gynecological survey · 2015Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPuerto Rican children share a disproportionate burden of prematurity and asthma in the United States. Little is known about prematurity and childhood asthma in Puerto Rican subjects.
objectiveWe sought to examine whether prematurity is associated with asthma in Puerto Rican children.
methodsWe performed a case-control study of 678 children aged 6 to 14 years with (n = 351) and without (n = 327) asthma living in San Juan, Puerto Rico. Prematurity was defined by parental report for our primary analysis. In a secondary analysis, we only included children whose parents reported prematurity that required admission to the neonatal intensive care unit. Asthma was defined as physician-diagnosed asthma and wheeze in the prior year. We used logistic regression for analysis. All multivariate models were adjusted for age, sex, household income, atopy (≥1 positive IgE level to common allergens), maternal history of asthma, and early-life exposure to environmental tobacco smoke.
resultsIn a multivariate analysis there was a significant interaction between prematurity and atopy on asthma (P = .006). In an analysis stratified by atopy, prematurity was associated with a nearly 5-fold increased odds of asthma in atopic children (adjusted odds ratio, 4.7; 95% CI, 1.5-14.3; P = .007). In contrast, there was no significant association between prematurity and asthma in nonatopic children. Similar results were obtained in our analysis of prematurity requiring admission to the neonatal intensive care unit and asthma.
conclusionsOur results suggest that atopy modifies the estimated effect of prematurity on asthma in Puerto Rican children. Prematurity might explain, in part, the high prevalence of atopic asthma in this ethnic group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.