Evidence map›Paper›PMID 24139397›Full record

ReviewCell host & microbe2013

Lipids in innate antiviral defense.

John W Schoggins, Glenn Randall

Abstract readReview
In one paragraph

Review in Cell host & microbe, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Green algaeNarra J · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John W SchogginsDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: john.schoggins@utsouthwestern.edu.
Glenn Randall

Funding

Hepatitis C Virus Trafficking in Infected HepatocytesR01AI080703 · NIAID · UNIVERSITY OF CHICAGO · PI RANDALL, GLENN C · 2010 to 2014
$1.7M
Hepatitits C Virus Trafficking in Infected HepatocytesR56AI080703 · NIAID · UNIVERSITY OF CHICAGO · PI RANDALL, GLENN C · 2009 to 2017
$777k
Interactions between type I and III interferon during resolution of HCV infectionK01DK095031 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI SCHOGGINS, JOHN W. · 2012 to 2016
$629k
Fatty Acid Synthase Inhibitors As Broad Spectrum Anti-Flaviviral TherapeuticsR21AI102236 · NIAID · UNIVERSITY OF CHICAGO · PI RANDALL, GLENN C · 2012 to 2013
$440k
NIAID NIH HHS AI080703NIAID NIH HHS AI102236NIAID NIH HHS R01 AI080703NIAID NIH HHS R21 AI102236NIAID NIH HHS R56 AI080703NIDDK NIH HHS DK095031NIDDK NIH HHS K01 DK095031
6 · The paper itself

Abstract

It is becoming apparent that infections by a major class of viruses, those with envelopes, can be inhibited during their entry at the step of fusion with cellular membranes. In this review, we discuss multiple innate immune mechanisms that have evolved to modify the lipid composition of cellular and viral membranes to inhibit virion fusion of enveloped viruses.

Indexed as

Immunity, InnateVirusesVirus InternalizationAnimalsHumansMembrane LipidsVirus DiseasesMembrane Lipids

Identifiers

PMID24139397
PMCPMC3850052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.