ArticleImmunity2013
An element of life: competition for zinc in host-pathogen interaction.
Article in Immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Zinc against COVID-19? Symptom surveillance and deficiency risk groups.PLoS neglected tropical diseases · 2021Review
- Cellular zinc homeostasis modulates polarization of THP-1-derived macrophages.European journal of nutrition · 2018Article
- Natural allelic variation of the AZI1 gene controls root growth under zinc-limiting condition.PLoS genetics · 2018Article
- Metallothioneins: Emerging Modulators in Immunity and Infection.International journal of molecular sciences · 2017Review
- Modulation of Zinc Homeostasis inFrontiers in microbiology · 2017Article
- Immunological orchestration of zinc homeostasis: The battle between host mechanisms and pathogen defenses.Archives of biochemistry and biophysics · 2016Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc homeostasis plays a plethora of different roles in the immune response. In this issue of Immunity, Vignesh et al. (2013) demonstrate that stimulation of macrophages with GM-CSF deprives intracellular Histoplasma capsulatum of zinc, improving pathogen clearance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.