ArticleOncology letters2013
TGFβ1 and HGF protein secretion by esophageal squamous epithelial cells and stromal fibroblasts in oesophageal carcinogenesis.
Article in Oncology letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
- Pathological examination of factors involved in PD-L1 expression in patients with oral tongue squamous cell carcinoma.Maxillofacial plastic and reconstructive surgery · 2024Article
- scDiffCoAM: A complete framework to identify potential biomarkers for esophageal squamous cell carcinoma using scRNA-Seq data analysis.Journal of biosciences · 2024Article
- The Role of Tumor Microenvironment in Invasion and Metastasis of Esophageal Squamous Cell Carcinoma.Frontiers in oncology · 2022Review
- Hepatocyte Growth Factor Overexpression Slows the Progression of 4NQO-Induced Oral Tumorigenesis.Frontiers in oncology · 2021Article
- Esophageal Microenvironment: From Precursor Microenvironment to Premetastatic Niche.Cancer management and research · 2020Review
- Esophageal Tumor Microenvironment.Advances in experimental medicine and biology · 2020Review
- Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-α.The Journal of allergy and clinical immunology · 2019Article
- Cancer-associated fibroblast regulation of tumor neo-angiogenesis as a therapeutic target in cancer.Oncology letters · 2019Review
- Upregulating MMP-1 in carcinoma-associated fibroblasts reduces the efficacy of Taxotere on breast cancer synergized by Collagen IV.Oncology letters · 2018Article
- Low Expression of Transforming Growth Factor β in the Epithelium of Barrett's Esophagus.Gastroenterology research · 2018Article
- Angiogenic factors: role in esophageal cancer, a brief review.Esophagus : official journal of the Japan Esophageal Society · 2018Review
- Inflammatory cytokines are associated with response and prognosis in patients with esophageal cancer.Oncotarget · 2017Article
- Oesophageal Stem Cells and Cancer.Advances in experimental medicine and biology · 2017Article
- The tumor microenvironment in esophageal cancer.Oncogene · 2016Review
- The role of cancer-associated fibroblasts in esophageal cancer.Journal of translational medicine · 2016Review
- Article
- High p-Smad2 expression in stromal fibroblasts predicts poor survival in patients with clinical stage I to IIIA non-small cell lung cancer.World journal of surgical oncology · 2014Article
- Expression of basic fibroblast growth factor, CD31, and α-smooth muscle actin and esophageal cancer recurrence after definitive chemoradiation.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- Transforming growth factor-β1 and α-smooth muscle actin in stromal fibroblasts are associated with a poor prognosis in patients with clinical stage I-IIIA nonsmall cell lung cancer after curative resection.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- Network based analyses of gene expression profile of LCN2 overexpression in esophageal squamous cell carcinoma.Scientific reports · 2014Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Esophageal squamous cell carcinoma (ESCC) is an aggressive cancer with a poor prognosis. Cancer-associated fibroblasts (CAFs) affect tumorigenesis by creating an environment primed for growth and invasion through the secretion of factors, including hepatocyte growth factor (HGF) and transforming growth factor β1 (TGFβ1). In the present study, the levels of α-smooth muscle actin (α-SMA), TGFβ1 and HGF were determined immunohistochemically in oesophageal precancerous lesions (low- and high-grade intraepithelial neoplasia; LGIEN and HGIEN, respectively), carcinoma
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