ArticleExperimental and therapeutic medicine2013
Pulmonary fat embolism and related effects during femoral intramedullary surgery: An experimental study in dogs.
Article in Experimental and therapeutic medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Bone cement implantation syndrome: a scoping review.British journal of anaesthesia · 2025Article
- Assessing Cardiopulmonary Safety of Intramedullary Bone Graft Harvesting: A Comparative Study of the RIA 2 System and the ARA Concept.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Incidence of deep vein thrombosis before and after total knee arthroplasty without pharmacologic prophylaxis: a 128-row multidetector CT indirect venography study.BMC musculoskeletal disorders · 2018Article
- Peritoneal dialysis treatment for severe lupus nephritis patients complicated with essential organ dysfunction.Experimental and therapeutic medicine · 2015Article
- An Experimental Study to Determine the Role of Inferior Vena Cava Filter in Preventing Bone Cement Implantation Syndrome.Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society · 2015Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to develop an animal model of pulmonary fat embolism (PFE) caused by femoral intramedullary procedures, and to investigate the initial changes in the hemodynamics, cytokines and risk factors of PFE. Sixteen dogs were randomly divided into two groups: Group A (intramedullary reaming and bone cement injection, n=8) and Group B (surgical approach without opening the medullary cavity, n=8). The hemodynamics, arterial blood gases and relevant cytokines were evaluated, and the lungs were examined using Oil Red O staining. In the animals of Group A, the heart rate, central venous pressure, mean pulmonary arterial pressure, pulmonary capillary wedge pressure and extravascular lung water (EVLW) were increased compared with the baseline levels, while the mean arterial pressure was decreased immediately following the reaming and bone cement infusion (P<0.05). Furthermore, there was a significant reduction in the pH and the arterial oxygen tension (PaO
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