Evidence map›Paper›PMID 24136759›Full record

ArticleEinstein (Sao Paulo, Brazil)

Short-term effects of moderate intensity physical activity in patients with metabolic syndrome.

Caroline Macoris Colombo, Rafael Michel de Macedo, Miguel Morita Fernandes-Silva, Alexandra Moro Caporal, Andréa Emilia Stinghen, Costantino Roberto Costantini, Cristina Pellegrino Baena, Luiz Cesar Guarita-Souza, José Rocha Faria-Neto

Abstract read
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Article in Einstein (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caroline Macoris Colombo
Rafael Michel de Macedo
Miguel Morita Fernandes-Silva
Alexandra Moro Caporal
Andréa Emilia Stinghen
Costantino Roberto Costantini
Cristina Pellegrino Baena
Luiz Cesar Guarita-Souza
José Rocha Faria-Neto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate whether a short-term moderate intensity exercise program could change inflammatory parameters, and improve different components of metabolic syndrome in sedentary patients.

methodsSixteen patients completed the 12-week program of supervised exercise, which consisted of a 40 to 50 minutes of walking, 3 times a week, reaching 50 to 60% of the heart rate reserve. The parameters evaluated before and after intervention were waist circumference, systolic and diastolic blood pressure, triglycerides, LDL cholesterol, HDL cholesterol, total cholesterol, C-reactive protein and interleukin 8.

resultsThere was a significant reduction in waist circumference (102.1±7.5cm to 100.8±7.4cm; p=0.03) and in body mass index (29.7±3.2kg/m² versus 29.3±3.5kg/m²; p=0.03). Systolic blood pressure dropped from 141±18 to 129±13mmHg and diastolic from 79±12 to 71±10mmHg (with p<0.05 for both). No changes were observed on total cholesterol, LDL cholesterol and triglycerides, although HDL cholesterol levels improved, from 45.5±6.0 to 49.5±9.8mg/dL (p=0.02). There was a trend toward reduction of C-reactive protein (8.3%; p=0.07) and interleukin 8 levels (17.4%; p=0.058). The improvement in cardiovascular capacity was demonstrated by an increase of 13% in estimated volume of oxygen (p<0.001).

conclusionBenefits of aerobic exercise of moderate intensity were seen within only 12 weeks of training in sedentary patients with metabolic syndrome. Considering the easy self-applicability and proven metabolic effects, an exercise program could be a first approach to sedentary patients with metabolic syndrome.

Indexed as

Blood PressureBody Mass IndexCholesterolC-Reactive ProteinExercise TherapyFemaleHeart RateHumansMaleMetabolic SyndromeMiddle AgedPilot ProjectsProspective StudiesSedentary BehaviorTreatment OutcomeTriglyceridesCholesterolC-Reactive ProteinTriglycerides

Identifiers

PMID24136759
PMCPMC4878591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.