Evidence map›Paper›PMID 24136363›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2013

Downstream clinical implications of abnormal myocardial perfusion single-photon emission computed tomography based on appropriate use criteria.

Farhan J Khawaja, Hayan Jouni, Todd D Miller, David O Hodge, Raymond J Gibbons

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Quality metrics for single-photon emission computed tomography myocardial perfusion imaging: an ASNC information statement.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  2. Raymond J Gibbons, MSc, MD (born 1949).Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  3. ASNC imaging guidelines for nuclear cardiology procedures : Standardized reporting of nuclear cardiology procedures.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  4. Outcomes after inappropriate nuclear myocardial perfusion imaging: A meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Review
  5. Article
  6. Clinical utility of inappropriate positron emission tomography myocardial perfusion imaging: test results and cardiovascular events.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  7. Myocardial perfusion imaging determination using an appropriate use smartphone application.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  8. The value and appropriateness of positron emission tomography: an evolving tale.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Farhan J KhawajaCenter for Interventional Vascular Therapy, Division of Cardiovascular Diseases, Department of Medicine, Columbia University Medical Center, New York, NY, USA.
Hayan Jouni
Todd D Miller
David O Hodge
Raymond J Gibbons

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAppropriate use criteria (AUC) for single-photon emission computed tomography myocardial perfusion images (SPECT-MPI) were developed to address the growth of cardiac imaging studies. However, these criteria have not been vigorously validated. We sought to determine the rate of abnormal stress SPECT-MPI studies and subsequent revascularization procedures as categorized by AUC.

methodsWe retrospectively examined 280 patients who underwent stress SPECT-MPI and categorized these studies as appropriate, inappropriate, or uncertain based on AUC. Data regarding subsequent angiography and revascularization within 6 months after stress SPECT-MPI were collected from the electronic medical record.

results280 patients met the inclusion criteria (mean age 67.3 ± 11.4 years, 36 % female). When categorized by AUC, 62.9 % (N = 176) of stress SPECT-MPI were considered appropriate, 13.6 % (N = 38) uncertain, and 23.6 % (N = 66) inappropriate. Appropriate stress SPECT-MPI studies were more likely to have intermediate or high risk results than uncertain or inappropriate studies [40 % (N = 71) vs. 21 % (N = 8) and 18 % (N = 12), respectively; P = 0.008)]. Appropriate studies were associated with an increased rate of coronary angiography [14 % (N = 25)] compared to the uncertain (0 %) and inappropriate [3 % (N = 2)] studies (P = 0.003). There was also an increased rate of revascularization after appropriate studies [9 % (N = 16)] compared to the uncertain (0 %) and inappropriate (0 %) studies (P = 0.006).

conclusionsAppropriate stress SPECT-MPI studies are more likely to result in abnormal results requiring subsequent revascularization compared to inappropriate and uncertain stress studies. Inappropriate and uncertain stress SPECT-MPI did not lead to subsequent revascularization.

Indexed as

Myocardial Perfusion ImagingTomography, Emission-Computed, Single-PhotonAdultAgedFemaleHumansMaleMiddle AgedMyocardial RevascularizationRetrospective Studies

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.