ArticleJournal of clinical psychopharmacology2014
Amphetamine increases errors during episodic memory retrieval.
Article in Journal of clinical psychopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- The relationship between novelty-seeking traits and behavior: Establishing construct validity for the human Behavioral Pattern Monitor.Psychiatry research · 2022Trial
- MDMA Impairs Both the Encoding and Retrieval of Emotional Recollections.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Trial
- Amphetamine increases activity but not exploration in humans and mice.Psychopharmacology · 2016Trial
- Intimate insight: MDMA changes how people talk about significant others.Journal of psychopharmacology (Oxford, England) · 2015Trial
- Amphetamine fails to alter cued recollection of emotional images: study of encoding, retrieval, and state-dependency.PloS one · 2014Trial
- Review
- The acute effects of psychoactive drugs on emotional episodic memory encoding, consolidation, and retrieval: A comprehensive review.Neuroscience and biobehavioral reviews · 2023Review
- Amphetamine Modulation of Long-Term Object Recognition Memory in Rats: Influence of Stress.Frontiers in pharmacology · 2021Article
- Dopamine is a double-edged sword: dopaminergic modulation enhances memory retrieval performance but impairs metacognition.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Article
- Making Sense of: Sensitization in Schizophrenia.The international journal of neuropsychopharmacology · 2017Review
- Stimulant drug effects on touchscreen automated paired-associates learning (PAL) in rats.Learning & memory (Cold Spring Harbor, N.Y.) · 2016Article
- False Memories for Affective Information in Schizophrenia.Frontiers in psychiatry · 2016Article
- Effects of Sulpiride on True and False Memories of Thematically Related Pictures and Associated Words in Healthy Volunteers.Frontiers in psychiatry · 2016Article
- Psychostimulants and movement disorders.Frontiers in neurology · 2015Review
- Effects of acute methamphetamine on emotional memory formation in humans: encoding vs consolidation.PloS one · 2015Article
- Amphetamines, new psychoactive drugs and the monoamine transporter cycle.Trends in pharmacological sciences · 2015Review
- Alcohol and pharmacologically similar sedatives impair encoding and facilitate consolidation of both recollection and familiarity in episodic memory.Cognitive neuroscienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Moderate doses of stimulant drugs are known to enhance memory encoding and consolidation, but their effects on memory retrieval have not been explored in depth. In laboratory animals, stimulants seem to improve retrieval of emotional memories, but comparable studies have not been carried out in humans. In the present study, we examined the effects of dextroamphetamine (AMP) on retrieval of emotional and unemotional stimuli in healthy young adults, using doses that enhanced memory formation when administered before encoding in our previous study. During 3 sessions, healthy volunteers (n = 31) received 2 doses of AMP (10 and 20 mg) and placebo in counterbalanced order under double-blind conditions. During each session, they first viewed emotional and unemotional pictures and words in a drug-free state, and then 2 days later their memory was tested, 1 hour after AMP or placebo administration. Dextroamphetamine did not affect the number of emotional or unemotional stimuli remembered, but both doses increased recall intrusions and false recognition. Dextroamphetamine (20 mg) also increased the number of positively rated picture descriptions and words generated during free recall. These data provide the first evidence that therapeutic range doses of stimulant drugs can increase memory retrieval errors. The ability of AMP to positively bias recollection of prior events could contribute to its potential for abuse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.