Evidence map›Paper›PMID 24135830›Full record

ArticleBiomatter

Synergetic inactivation of Staphylococcus epidermidis and Streptococcus mutansin a TiO2/H2O2/UV system.

Erik Unosson, Eleni K Tsekoura, Håkan Engqvist, Ken Welch

Open access · bronzeAbstract read
In one paragraph

Article in Biomatter. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Development of Antibacterial Ti-CuMaterials (Basel, Switzerland) · 2019
    Article
  3. Effect of Copper Ion Concentration on Bacteria and Cells.Materials (Basel, Switzerland) · 2019
    Article
  4. Article
  5. Early Biofilm Formation on UV Light Activated Nanoporous TiOInternational journal of biomaterials · 2018
    Article
  6. Debridement of Bacterial Biofilms with TiOInternational journal of biomaterials · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Erik UnossonDivision of Applied Materials Science; Department of Engineering Sciences; The Ångström Laboratory; Uppsala University; Uppsala, Sweden.
Eleni K TsekouraDivision of Nanotechnology and Functional Materials; Department of Engineering Sciences; The Ångström Laboratory; Uppsala University; Uppsala, Sweden.
Håkan EngqvistDivision of Applied Materials Science; Department of Engineering Sciences; The Ångström Laboratory; Uppsala University; Uppsala, Sweden.
Ken WelchDivision of Nanotechnology and Functional Materials; Department of Engineering Sciences; The Ångström Laboratory; Uppsala University; Uppsala, Sweden.
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TiO 2 photocatalysis can be used to kill surface adherent bacteria on biomaterials, and is particularly interesting for use with percutaneous implants and devices. Its efficiency and safety, however, depend on the activation energy required. This in vitro study investigates synergetic effects against the clinically relevant strains S. epidermidis and S. mutans when combining photocatalytic surfaces with H2O2. After 20 min exposure to 0.1 wt% H2O2 and UV light on TiO2 surfaces, viabilities of S. epidermidis and S. mutans were reduced by 99.7% and 98.9%, respectively. Without H2O2 the corresponding viability reduction was 86% for S. epidermidis and 65% for S. mutans. This study indicates that low concentrations of H2O2 can enhance the efficiency of photocatalytic TiO2 surfaces, which could potentially improve current techniques used for decontamination and debridement of TiO2 coated biomedical implants and devices.

Indexed as

Cell SurvivalCoated Materials, BiocompatibleDisinfectionDrug SynergismHydrogen PeroxideMaterials TestingMicrobial ViabilityStaphylococcus epidermidisStreptococcus mutansSurface PropertiesTitaniumUltraviolet RaysCoated Materials, BiocompatibleHydrogen PeroxideTitaniumtitanium dioxideantibacterialhydrogen peroxidephotocatalysisphotolysissynergytitanium dioxideUV light

Identifiers

PMID24135830
PMCPMC3866197
OpenAlexW2110777374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.