Evidence map›Paper›PMID 24135421›Full record

ArticleJournal of shoulder and elbow surgery2014

Treatment choice affects inpatient adverse events and mortality in older aged inpatients with an isolated fracture of the proximal humerus.

Valentin Neuhaus, Arjan G J Bot, Christiaan H J Swellengrebel, Nitin B Jain, Jon J P Warner, David C Ring

Open access · greenAbstract read
In one paragraph

Article in Journal of shoulder and elbow surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Mortality in patients over 65 with proximal humerus fractures: a systematic review of 414,379 shoulders with meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
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  11. Analysis of predictors of mortality after surgical and non-surgical management in proximal humerus fractures.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021
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  18. ORIF versus arthroplasty for open proximal humerus fractures: Nationwide Inpatient Sample data between 1998 and 2013.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2018
    Article
  19. Predictors of Mortality in Elder Patients With Proximal Humeral Fracture.Geriatric orthopaedic surgery & rehabilitation · 2018
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Valentin NeuhausOrthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA, USA.
Arjan G J BotOrthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA, USA.
Christiaan H J SwellengrebelOrthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA, USA.
Nitin B JainDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA, USA; Harvard Shoulder Service, Massachusetts General Hospital, Boston, MA, USA; Department of Orthopedics, Brigham and Women's Hospital, Boston, MA, USA.
Jon J P WarnerHarvard Shoulder Service, Massachusetts General Hospital, Boston, MA, USA.
David C RingOrthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA, USA. Electronic address: dring@partners.org.
Massachusetts General Hospital · USHarvard University · USSpaulding Rehabilitation Hospital · US

Funding

Rotator Cuff Tears: Optimizing Diagnosis and Treatment StrategiesK23AR059199 · NIAMS · VANDERBILT UNIVERSITY · PI JAIN, NITIN B · 2010 to 2014
$650k
NIAMS NIH HHS 1K23AR059199NIAMS NIH HHS K23 AR059199
6 · The paper itself

Abstract

backgroundThis study tests the null hypothesis that, among patients aged 65 and older admitted to a United States hospital with an isolated fracture of the proximal humerus (no other injuries or fractures), there are no differences between operative (fixation or arthroplasty) and nonoperative treatments with respect to inpatient adverse events, inpatient mortality, and discharge to a long-term care facility rates accounting for comorbidities.

methodsUsing a large national database representing an estimated 132,005 patients aged 65 and older admitted to a US hospital with an isolated proximal humerus fracture between 2003 and 2007. Sixty-one percent did not have surgery, 22% were treated with open reduction and internal fixation (ORIF), and 17% were treated with arthroplasty.

resultsThe risk of an in hospital adverse event was 21% overall and was 4.4 times greater with arthroplasty and 2.7 times greater with ORIF compared to nonoperative treatment. The risk of in hospital death was 1.8% overall and was 2.8 times greater with ORIF compared to nonoperative treatment. Patients treated operatively were less likely to be discharged to a long-term facility compared to patients treated nonoperatively.

conclusionIn spite of a tendency to treat the most infirm patients (those that are not discharged to home) nonoperatively, operative treatment (open reduction and internal fixation in particular) is an independent risk factor for inpatient adverse events and mortality in older-aged patients admitted to the hospital with an isolated fracture of the proximal humerus and should perhaps be offered more judiciously. LEVEL OF EVIDENCE: Level III, retrospective cohort study, treatment study.

Indexed as

AgedAged, 80 and overArthroplasty, ReplacementCohort StudiesDatabases, FactualFemaleFracture Fixation, InternalHospitalizationHumansMaleRetrospective StudiesRisk FactorsShoulder FracturesShoulder JointTreatment OutcomeUnited StatesarthroplastyComorbiditycomplicationopen reduction and internal fixationoperationproximal humerus fracturesurgery

Identifiers

PMID24135421
PMCPMC4239693
OpenAlexW2147014461

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.