Evidence map›Paper›PMID 24135226›Full record

ArticleDevelopmental cell2013

Sculpting the nucleus with dynamic microtubules.

Yuxuan Guo, Yixian Zheng

Open access · bronzeAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Vimentin Association with Nuclear Grooves in Normal MEF 3T3 Cells.International journal of molecular sciences · 2020
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuxuan GuoDepartment of Biology, Johns Hopkins University, Baltimore, MD 21218, USA; Department of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA.
Yixian Zheng
Johns Hopkins University · US

Funding

Super-resolution microscopy of nuclear lamin and spindle envelope/matrix functionR01GM106023 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI GOLDMAN, ROBERT D, ZHENG, YIXIAN · 2013 to 2020
$3.5M
The function and assembly of the lamin-B spindle sheathR01GM056312 · NIGMS · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI ZHENG, YIXIAN · 1997 to 2014
$2.7M
NIGMS NIH HHS R01 GM056312NIGMS NIH HHS R01-GM056312NIGMS NIH HHS R01 GM106023NIGMS NIH HHS R01-GM106023
6 · The paper itself

Abstract

How nuclear morphology is regulated during development and disease remains poorly understood. In this issue of Developmental Cell, using a pronuclear assembly assay, Xue et al. (2013) demonstrate that Dppa2, a chromatin-bound microtubule regulator, controls both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.

Indexed as

AnimalsCell NucleusChromatinMicrotubulesNuclear ProteinsXenopus ProteinsChromatinDppa2 protein, XenopusNuclear ProteinsXenopus Proteins

Identifiers

PMID24135226
PMCPMC5439145
OpenAlexW2045437615

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.