ArticleGenome medicine2013
The Coriell personalized medicine collaborative pharmacogenomics appraisal, evidence scoring and interpretation system.
Article in Genome medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of SLCO1B1 Pharmacogenetic Testing on Patient and Healthcare Outcomes: A Systematic Review.Clinical pharmacology and therapeutics · 2019Pooled it
- BioFRAM PGx, an Implementation Proposal for Pharmacogenetics in the Spanish National Health System.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Star allele search: a pharmacogenetic annotation database and user-friendly search tool of publicly available 1000 Genomes Project biospecimens.BMC genomics · 2024Article
- ursaPGx: a new R package to annotate pharmacogenetic star alleles using phased whole-genome sequencing data.Frontiers in bioinformatics · 2024Article
- Maturing pharmacogenomic factors deliver improvements and cost efficiencies.Cambridge prisms. Precision medicine · 2023Review
- Patient Perceptions and Potential Utility of Pharmacogenetic Testing in Chronic Pain Management and Opioid Use Disorder in the Camden Opioid Research Initiative.Pharmaceutics · 2022Article
- Real-World Impact of a Pharmacogenomics-Enriched Comprehensive Medication Management Program.Journal of personalized medicine · 2022Article
- Common Treatment, Common Variant: Evolutionary Prediction of Functional Pharmacogenomic Variants.Journal of personalized medicine · 2021Article
- Pharmacogenomic (PGx) Counseling: Exploring Participant Questions about PGx Test Results.Journal of personalized medicine · 2020Article
- The ACCOuNT Consortium: A Model for the Discovery, Translation, and Implementation of Precision Medicine in African Americans.Clinical and translational science · 2019Review
- Operationalizing the Reciprocal Engagement Model of Genetic Counseling Practice: a Framework for the Scalable Delivery of Genomic Counseling and Testing.Journal of genetic counseling · 2018Article
- Evidence-based prioritisation and enrichment of genes interacting with metformin in type 2 diabetes.Diabetologia · 2017Article
- The Routine Clinical use of Pharmacogenetic Tests: What it Will Require?Pharmaceutical research · 2017Review
- Assessment of pharmacogenetic tests: presenting measures of clinical validity and potential population impact in association studies.The pharmacogenomics journal · 2017Article
- Big Data Analytics for Genomic Medicine.International journal of molecular sciences · 2017Review
- Precision Military Medicine: Conducting a multi-site clinical utility study of genomic and lifestyle risk factors in the United States Air Force.NPJ genomic medicine · 2017Article
- Challenges in Translating GWAS Results to Clinical Care.International journal of molecular sciences · 2016Article
- An expanded pharmacogenomics warfarin dosing table with utility in generalised dosing guidance.Thrombosis and haemostasis · 2016Observational
- Other side of the coin for personalised medicine and healthcare: content analysis of 'personalised' practices in the literature.BMJ open · 2016Article
- Challenges of Identifying Clinically Actionable Genetic Variants for Precision Medicine.Journal of healthcare engineering · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Implementation of pharmacogenomics (PGx) in clinical care can lead to improved drug efficacy and reduced adverse drug reactions. However, there has been a lag in adoption of PGx tests in clinical practice. This is due in part to a paucity of rigorous systems for translating published clinical and scientific data into standardized diagnostic tests with clear therapeutic recommendations. Here we describe the Pharmacogenomics Appraisal, Evidence Scoring and Interpretation System (PhAESIS), developed as part of the Coriell Personalized Medicine Collaborative research study, and its application to seven commonly prescribed drugs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.