Evidence map›Paper›PMID 24134716›Full record

ReviewClinical and experimental immunology2014

Multiple sclerosis treatment and infectious issues: update 2013.

A Winkelmann, M Loebermann, E C Reisinger, U K Zettl

Open access · greenAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 43 citations in OpenAlex.

  1. Nasal Mucociliary Clearance and Its Relationship With Disease Severity in Patients With Multiple Sclerosis.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  2. Review
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  12. Peptide-Conjugated Nanoparticles Reduce Positive Co-stimulatory Expression and T Cell Activity to Induce Tolerance.Molecular therapy : the journal of the American Society of Gene Therapy · 2017
    Article
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  15. Review
  16. Article
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  19. Review
  20. Monoclonal antibodies in treatment of multiple sclerosis.Clinical and experimental immunology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A WinkelmannDepartment of Neurology, University of Rostock, Rostock, Germany.
M Loebermann
E C Reisinger
U K Zettl
University of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunomodulation and immunosuppression are generally linked to an increased risk of infection. In the growing field of new and potent drugs for multiple sclerosis (MS), we review the current data concerning infections and prevention of infectious diseases. This is of importance for recently licensed and future MS treatment options, but also for long-term established therapies for MS. Some of the disease-modifying therapies (DMT) go along with threats of specific severe infections or complications, which require a more intensive long-term monitoring and multi-disciplinary surveillance. We update the existing warning notices and infectious issues which have to be considered using drugs for multiple sclerosis.

Indexed as

HumansImmunologic FactorsInfection ControlInfectionsMultiple SclerosisImmunologic Factorsdisease-modifying treatmentimmunosuppressioninfectionmultiple sclerosisside effects

Identifiers

PMID24134716
PMCPMC3927903
OpenAlexW1521435570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.