ArticleDeutsches Arzteblatt international2013
Adult patients with nosocomial pneumonia: epidemiology, diagnosis, and treatment.
Article in Deutsches Arzteblatt international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02427633 (A Randomised Controlled Study of the Use of Recovery Positions for Comatose Patients in a Resource Limited Setting), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomised Controlled Study of the Use of Recovery Positions for Comatose Patients in a Resource Limited Setting
Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Risk Factors and Medical Burden of Multidrug-Resistant Organism Infection in Hospitalized Patients with Pneumonia.Infection and drug resistance · 2026Article
- Predictive Factors for the Need of Tracheostomy in Patients With Large Vessel Occlusion Stroke Being Treated With Mechanical Thrombectomy.Frontiers in neurology · 2021Article
- [Postcardiac arrest treatment guide].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2020Review
- Hot topics and current controversies in community-acquired pneumonia.Breathe (Sheffield, England) · 2019Review
- Chinese guidelines for the diagnosis and treatment of hospital-acquired pneumonia and ventilator-associated pneumonia in adults (2018 Edition).Journal of thoracic disease · 2019Review
- Pneumonia in severely injured patients with thoracic trauma: results of a retrospective observational multi-centre study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2019Observational
- Gastrointestinal endoscopy under sedation is associated with pneumonia in older inpatients-results of a retrospective case-control study.United European gastroenterology journal · 2018Article
- Influence of beta-blocker therapy on the risk of infections and death in patients at high risk for stroke induced immunodepression.PloS one · 2018Article
- [Antibiotic Stewardship 2.0. Individualization of therapy].Der Internist · 2017Review
- Potency of parenteral antimicrobials including ceftolozane/tazobactam against nosocomial respiratory tract pathogens: considerations for empiric and directed therapy.Journal of thoracic disease · 2017Article
- [Nosocomial pneumonia from a radiological perspective].Der Radiologe · 2017Review
- [Severe pneumonia in the intensive care unit].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2016Review
- Detection of Enterococcus spp. in bronchoalveolar lavage fluid of patients with high-risk neutropenia: May it be ignored?Journal of cancer research and clinical oncology · 2016Article
- Current and Future Considerations for the Treatment of Hospital-Acquired Pneumonia.Advances in therapy · 2016Review
- The Reduction in Antibiotic Use in Hospitals.Deutsches Arzteblatt international · 2015Article
- Imaging in the diagnosis of lung disease: more sophisticated methods require greater interdisciplinary collaboration.Deutsches Arzteblatt international · 2014Article
- In reply.Deutsches Arzteblatt international · 2014Article
- The crucial role of molecular diagnostics.Deutsches Arzteblatt international · 2014Article
- Nosocomial infections - a present and future challenge.Deutsches Arzteblatt international · 2013Article
Corrections and comments
- Commented on by
- Commented on byIn reply.2014
- Commented on by
Authors and funding
30 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNosocomial pneumonia is among the most common types of infection in hospitalized patients. The increasing prevalence of multi-drug resistant organisms (MDROs) in recent years points to the need for an up-to-date clinical guideline.
methodsAn interdisciplinary S3 guideline was created on the basis of a systematic literature review in the PubMed and Cochrane Library databases, with assessment and grading of the evidence according to the GRADE system.
results9097 abstracts and 808 articles were screened in full text, and 22 recommendations were issued. It is recommended that any antimicrobial treatment should be preceded by a microbiological diagnostic evaluation with cultures of blood and respiratory samples. The diagnosis of nosocomial pneumonia should be suspected in any patient with a new or worsened pulmonary infiltrate who meets any two of the following three criteria: leucocyte count above 10,000 or below 4000/µL, temperature above 38.3°C, and/or the presence of purulent respiratory secretions. The initially calculated antimicrobial treatment should be begun without delay; it should be oriented to the locally prevailing resistance pattern, and its intensity should be a function of the risk of infection with MDROs. The initial treatment should be combination therapy if there is a high risk of MDRO infection and/or if the patient is in septic shock. In the new guideline, emphasis is laid on a strict de-escalation concept. In particular, antimicrobial treatment usually should not be continued for longer than eight days.
conclusionThe new guideline's recommendations are intended to encourage rational use of antibiotics, so that antimicrobial treatment will be highly effective while the unnecessary selection of multi-drug-resistant organisms will be avoided.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.