ReviewClinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases2013
Painful prosthesis: approaching the patient with persistent pain following total hip and knee arthroplasty.
Review in Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- Air entrapment resembling necrotising fasciitis as a frequent incident following total hip arthroplasty.Scientific reports · 2019Trial
- An evaluation of the diagnostic performance of the triphasic bone scintigraphy in patients suspected of aseptic total knee arthroplasty loosening.Journal of orthopaedics · 2025Article
- Bone Density May Be a Promising Predictor for Blood Loss during Total Hip Arthroplasty.Journal of clinical medicine · 2022Article
- Diagnosis of Central Sensitization and Its Effects on Postoperative Outcomes following Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Review
- Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening.European journal of hybrid imaging · 2021Article
- Pro-osteogenic Effects of WNT in a Mouse Model of Bone Formation Around Femoral Implants.Calcified tissue international · 2021Article
- [End-of-stem pain in hip and knee arthroplasty].Der Orthopade · 2021Review
- Urine Aluminum Concentration as a Possible Implant Biomarker ofACS omega · 2019Article
- Microbiological and Cellular Evaluation of a Fluorine-Phosphorus-Doped Titanium Alloy, a Novel Antibacterial and Osteostimulatory Biomaterial with Potential Applications in Orthopedic Surgery.Applied and environmental microbiology · 2019Article
- Chronic pain after total knee arthroplasty.EFORT open reviews · 2018Article
- Monitoring osseointegrated prosthesis loosening and fracture using electrical capacitance tomography.Biomedical engineering letters · 2018Article
- Correlations between inflammatory cytokines, muscle damage markers and acute postoperative pain following primary total knee arthroplasty.BMC musculoskeletal disorders · 2017Article
- Hypersensitivity reactions to metal implants: laboratory options.BMC musculoskeletal disorders · 2016Article
- Hip arthroscopy outcomes, complications, and traction safety in patients with prior lower-extremity arthroplasty.International orthopaedics · 2015Article
- A prospective study concerning the relationship between metal allergy and post-operative pain following total hip and knee arthroplasty.International orthopaedics · 2014Article
- Pathogenesis and clinical aspects of pain in patients with osteoporosis.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases · 2014Review
- CHANGES IN BONE MINERAL DENSITY AFTER TOTAL KNEE ARTHROPLASTY.Acta ortopedica brasileiraArticle
- Densitometric evaluation of bone-prosthetic counterface in hip and knee arthroplasty with modern implants.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal DiseasesArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSymptomatic severe osteoarthritis and hip osteoporotic fractures are the main conditions requiring total hip arthroplasty (THA), whereas total knee arthroplasty (TKA) is mainly performed for pain, disability or deformity due to osteoarthritis. After surgery, some patients suffer from "painful prosthesis", which currently represents a clinical problem.
methodsA systematic review of scientific literature has been performed. A panel of experts has examined the issue of persistent pain following total hip or knee arthroplasty, in order to characterize etiopathological mechanisms and define how to cope with this condition.
resultsFour major categories (non infective, septic, other and idiopathic causes) have been identified as possible origin of persistent pain after total joint arthroplasty (TJA). Time to surgery, pain level and function impairment before surgical intervention, mechanical stress following prosthesis implant, osseointegration deficiency, and post-traumatic or allergic inflammatory response are all factors playing an important role in causing persistent pain after joint arthroplasty. Diagnosis of persistent pain should be made in case of post-operative pain (self-reported as VAS ≥3) persisting for at least 4 months after surgery, or new onset of pain (VAS ≥3) after the first 4 months, lasting ≥2 months. Acute pain reported as VAS score ≥7 in patients who underwent TJA should be always immediately investigated.
conclusionsThe cause of pain needs always to be indentified and removed whenever possible. Implant revision is indicated only when septic or aseptic loosening is diagnosed. Current evidence has shown that peri-and/or post-operative administration of bisphosphonates may have a role in pain management and periprosthetic bone loss prevention.
Indexed as
Identifiers
24133526PMC3797010W2205566382What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.