ReviewFrontiers in physiology2013
Emerging roles of mitochondria in the evolution, biogenesis, and function of peroxisomes.
Review in Frontiers in physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 76 citations in OpenAlex.
- Quantitative optical nanoscopy of mitochondrial-derived vesicles in neurons classifies pre-peroxisomal and clearing organelles.Nature communications · 2026Article
- ACOX-driven peroxisomal heterogeneity and functional compartmentalization in brown adipocytes of hypothyroid rats.Royal Society open science · 2023Article
- Review
- Hypothyroidism Intensifies Both Canonic and theCells · 2021Article
- Increased expression of fragmented tRNA promoted neuronal necrosis.Cell death & disease · 2021Article
- High-resolution Fourier light-field microscopy for volumetric multi-color live-cell imaging.Optica · 2021Article
- One ring to bring them all and in the darkness bind them: The trafficking of heme without deliverers.Biochimica et biophysica acta. Molecular cell research · 2021Review
- Genomic innovation of ATD alleviates mistranslation associated with multicellularity in Animalia.eLife · 2020Article
- Distinct Contributions of the Peroxisome-Mitochondria Fission Machinery During Sexual Development of the FungusFrontiers in microbiology · 2020Article
- Communication between mitochondria and other organelles: a brand-new perspective on mitochondria in cancer.Cell & bioscience · 2019Review
- Aberrant Drp1-mediated mitochondrial division presents in humans with variable outcomes.Human molecular genetics · 2018Article
- Unbalanced lipolysis results in lipotoxicity and mitochondrial damage in peroxisome-deficientMolecular biology of the cell · 2018Article
- Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights.Biological chemistry · 2018Review
- Identification of novel mitochondrial localization signals in human Tafazzin, the cause of the inherited cardiomyopathic disorder Barth syndrome.Journal of molecular and cellular cardiology · 2018Article
- The respiratory chain inhibitor rotenone affects peroxisomal dynamics via its microtubule-destabilising activity.Histochemistry and cell biology · 2017Article
- Pex35 is a regulator of peroxisome abundance.Journal of cell science · 2017Article
- Article
- Biallelic Mutations in DNM1L are Associated with a Slowly Progressive Infantile Encephalopathy.Human mutation · 2016Article
- ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis.Molecular endocrinology (Baltimore, Md.) · 2016Article
- High Light Intensity Leads to Increased Peroxule-Mitochondria Interactions in Plants.Frontiers in cell and developmental biology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last century peroxisomes were thought to have an endosymbiotic origin. Along with mitochondria and chloroplasts, peroxisomes primarily regulate their numbers through the growth and division of pre-existing organelles, and they house specific machinery for protein import. These features were considered unique to endosymbiotic organelles, prompting the idea that peroxisomes were key cellular elements that helped facilitate the evolution of multicellular organisms. The functional similarities to mitochondria within mammalian systems expanded these ideas, as both organelles scavenge peroxide and reactive oxygen species, both organelles oxidize fatty acids, and at least in higher eukaryotes, the biogenesis of both organelles is controlled by common nuclear transcription factors of the PPAR family. Over the last decade it has been demonstrated that the fission machinery of both organelles is also shared, and that both organelles act as critical signaling platforms for innate immunity and other pathways. Taken together it is clear that the mitochondria and peroxisomes are functionally coupled, regulating cellular metabolism and signaling through a number of common mechanisms. However, recent work has focused primarily on the role of the ER in the biogenesis of peroxisomes, potentially overshadowing the critical importance of the mitochondria as a functional partner. In this review, we explore the mechanisms of functional coupling of the peroxisomes to the mitochondria/ER networks, providing some new perspectives on the potential contribution of the mitochondria to peroxisomal biogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.