ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2013
Clinical profile of acute kidney injury in a pediatric intensive care unit from Southern India: A prospective observational study.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Systematic Literature Review on the Incidence and Prevalence of Heart Failure in Children and Adolescents.Pediatric cardiology · 2018Pooled it
- Acute kidney injury in critically ill children: Incidence, severity, and clinical outcomes from a quaternary pediatric intensive care unit in an upper-middle-income country.Pediatric nephrology (Berlin, Germany) · 2026Article
- Outcomes and mortality risk in children with acute kidney injury requiring dialysis and mechanical ventilation: an observational study from a pediatric nephrology critical care unit.Pediatric nephrology (Berlin, Germany) · 2026Observational
- Efficacy of Kidney Support Therapy in Critically Sick Children with Acute Kidney Injury: A Cross-Sectional Study.Indian pediatrics · 2026Article
- Evaluating the impact of change of the reference value of serum creatinine in the diagnosis, staging and outcome of acute kidney injury in critically ill children: an exploratory study.Journal of nephrology · 2025Article
- Epidemiology and outcome of pediatric acute kidney injury-multicenter observational study from a low-middle-income country.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Experience of continuous kidney replacement therapy in a tertiary care unit of a lower-middle-income country.Pediatric nephrology (Berlin, Germany) · 2025Article
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- Prevalence, risk factors, and outcomes of acute kidney injury in a pediatric cardiac intensive care unit: A cross-sectional study.Health science reports · 2024Article
- Transplanting the Liver for a New Life: Can the Kidney Throw in a Spanner?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- ROCK2 knockdown alleviates LPS-induced inflammatory injury and apoptosis of renal tubular epithelial cells via the NF-κB/NLRP3 signaling pathway.Experimental and therapeutic medicine · 2022Article
- Etiology, Clinical Profile, and Short-Term Outcome of Children With Acute Kidney Injury.Cureus · 2022Article
- Incidence, Risk Factors, the Role of Plasma NGAL and Outcome of Contrast-Induced Acute Kidney Injury in Critically Ill Children.Indian journal of pediatrics · 2021Article
- Clinical Profile and Short-Term Outcomes of Acute Kidney Injury in Patients Admitted to a Teaching Hospital in Ethiopia: A Prospective Study.International journal of nephrology and renovascular disease · 2021Article
- Management of Acute Kidney Injury in the Setting of Acute Respiratory Distress Syndrome: Review Focusing on Ventilation and Fluid Management Strategies.Journal of clinical medicine research · 2020Review
- Acute kidney injury in the pediatric intensive care unit at a tertiary care hospital of the Armed Forces: a cross-sectional observational study.Medical journal, Armed Forces India · 2020Article
- Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Predictors of Mortality in Acute Kidney Injury Patients Admitted to Medicine Intensive Care Unit in a Rural Tertiary Care Hospital.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2018Article
- Recognition and management of acute kidney injury in children: The ISN 0by25 Global Snapshot study.PloS one · 2018Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough the term acute renal failure was replaced by acute kidney injury (AKI) recently, there is a paucity of data on the incidence and profile of AKI in critically ill children from the developing world.
objectivesThe objective of this study is to determine the incidence, etiology, short term outcome and predictors of fatality in critically ill children admitted to the pediatric intensive care unit (PICU) with AKI, aged 1 month to 13 years. MATERIALS AND
methodsIn this prospective observational study, from June 2010 to March 2011, 215 children admitted to the PICU were screened for AKI, defined according to the AKI Network criteria. The patients with AKI were followed-up until discharge/death. Their clinical and biochemical data were recorded.
resultsThe incidence of AKI among 215 patients screened was 54 (25.1%). The common etiologies were infections, [34 (62.9%)], acute glomerulonephritis (7.6%), snake envenomation (5.7%), hemolytic uremic syndrome (3.8%) and congestive cardiac failures (3.8%). Among infections, pneumonia and septicemia constituted 26.5% each, meningoencephalitis accounted for 23.5%, and dengue, scrub typhus, tuberculosis and malaria constituted 9.3% of children with AKI. 27.8% of patients required dialysis. Overall mortality was 46.3%. On logistic regression analysis, requirement of mechanical ventilation was an independent predictor of fatality in AKI.
conclusionsBesides the high incidence of AKI in critically ill-children admitted to the PICU (25.1%), the condition was associated with adverse outcomes, including high mortality (46.3%) and need for dialysis (27.8%). Infections dominated the etiological profile. Requirement of mechanical ventilation predicted an adverse outcome in our patient population.
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