ArticleJournal of experimental zoology. Part A, Ecological genetics and physiology2014
Resveratrol and food effects on lifespan and reproduction in the model crustacean Daphnia.
Article in Journal of experimental zoology. Part A, Ecological genetics and physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Anti-Aging Effects of Quercetin in CladoceraACS omega · 2023Article
- Antiaging agents: safe interventions to slow aging and healthy life span extension.Natural products and bioprospecting · 2022Review
- Article
- Relationship between oxidative stress and lifespan in Daphnia pulex.Scientific reports · 2022Article
- Prospective Pharmacological Potential of Resveratrol in Delaying Kidney Aging.International journal of molecular sciences · 2021Review
- Article
- Article
- Genome-wide methylation is modified by caloric restriction in Daphnia magna.BMC genomics · 2019Article
- Dietary resveratrol increases mid-life fecundity of female Nothobranchius guentheri.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- Effects of fluctuating temperature and food availability on reproduction and lifespan.Experimental gerontology · 2016Article
- Article
- Invertebrates as model organisms for research on aging biology.Invertebrate reproduction & development · 2015Article
- Telomerase activity and telomere length in Daphnia.PloS one · 2015Article
- Effects of early life exposure to methylmercury in Daphnia pulex on standard and reduced food ration.Reproductive toxicology (Elmsford, N.Y.) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Longevity is a highly variable life history trait and its variation is attributable to both genetic and environmental factors. Exploring well-known environmental factors in a new model system is a useful approach to explore taxonomic variation in plasticity of longevity. We examined responsiveness of the Daphnia pulex clone TCO to potentially related interventions that have been reported to extend lifespan: resveratrol and dietary restriction. First, we examined effects of resveratrol on lifespan and fecundity in TCO which were grown at moderate (12K cells Ankistrodesmus falcatus mL⁻¹) and high (20K cells A. falcatus mL⁻¹) food levels. We found no evidence for lifespan extension by resveratrol, but found a reduction of lifetime fecundity. The effect of resveratrol on fecundity was more pronounced early in life. We then conducted an additional life table to test the effect of dietary restriction on TCO. Surprisingly, reduced food level did not extend the lifespan of TCO, which contrasts with previous studies in D. pulex. Our results suggest that variation in the response to dietary restriction might be more common than previously thought. If resveratrol activates genes involved in the response to dietary restriction, genetic polymorphisms in dietary restriction will influence responses to resveratrol. Thus, this experiment suggests that careful re-examination of resveratrol effects using diverse genotypes is required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.