ReviewAmerican journal of physiology. Cell physiology2014
Physical biology in cancer. 2. The physical biology of circulating tumor cells.
Review in American journal of physiology. Cell physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Microfluidics-based cell recognition through optimizing suspended cell staining techniques and artificial intelligence.Journal of biological engineering · 2026Article
- Circulating tumor cells in breast cancer bone metastasis: mechanisms, clinical relevance, and future directions.Cell death discovery · 2025Review
- Article
- Mesenchymal and Phosphatase of Regenerating Liver-3 Status in Circulating Tumor Cells May Serve as a Crucial Prognostic Marker for Assessing Relapse or Metastasis in Postoperative Patients With Colorectal Cancer.Clinical and translational gastroenterology · 2020Observational
- Impact of Polypharmacy for Chronic Ailments in Colon Cancer Patients: A Review Focused on Drug Repurposing.Cancers · 2020Review
- Trends in Bone Metastasis Modeling.Cancers · 2020Review
- The Engagement Between MDSCs and Metastases: Partners in Crime.Frontiers in oncology · 2020Review
- Circulating Tumor Cells: High-Throughput Imaging of CTCs and Bioinformatic Analysis.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2020Review
- Never Travel Alone: The Crosstalk of Circulating Tumor Cells and the Blood Microenvironment.Cells · 2019Review
- New Advances in the Study of Bone Tumors: A Lesson From the 3D Environment.Frontiers in physiology · 2019Article
- Advances in tumor-endothelial cells co-culture and interaction on microfluidics.Journal of pharmaceutical analysis · 2018Review
- Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations.Diagnostics (Basel, Switzerland) · 2018Review
- Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis.Frontiers in medicine · 2018Review
- Platelet count as a predictor of metastasis and venous thromboembolism in patients with cancer.Convergent science physical oncology · 2017Article
- Biophysical isolation and identification of circulating tumor cells.Lab on a chip · 2017Article
- Aspirin therapy reduces the ability of platelets to promote colon and pancreatic cancer cell proliferation: Implications for the oncoprotein c-MYC.American journal of physiology. Cell physiology · 2017Article
- Circulating Tumor Cells: Moving Biological Insights into Detection.Theranostics · 2017Review
- The Initial Detection and Partial Characterization of Circulating Tumor Cells in Neuroendocrine Prostate Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2016Article
- Circulating Tumor Cells: When a Solid Tumor Meets a Fluid Microenvironment.Advances in experimental medicine and biology · 2016Article
- A physical sciences network characterization of circulating tumor cell aggregate transport.American journal of physiology. Cell physiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The identification, isolation, and characterization of circulating tumor cells (CTCs) promises to enhance our understanding of the evolution of cancer in humans. CTCs provide a window into the hematogenous, or "fluid phase," of cancer, underlying the metastatic transition in which a locally contained tumor spreads to other locations in the body through the bloodstream. With the development of sensitive and specific CTC identification and isolation methodologies, the role of CTCs in clinical diagnostics, disease surveillance, and the physical basis of metastasis continues to be established. This review focuses on the quantification of the basic biophysical properties of CTCs and the use of these metrics to understand the hematogenous dissemination of these enigmatic cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.