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ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2014

Dental health of young children prenatally exposed to buprenorphine. A concern of child neglect?

K Kivistö, H Alapulli, S Tupola, S Alaluusua, S Kivitie-Kallio

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Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Buprenorphine enhancesJournal of oral microbiology · 2026
    Article
  2. Utilizing the Brief Child Abuse Potential Inventory in a cohort of children with early childhood caries.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

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5 · Who and what money

Authors and funding

5 authors.

K KivistöDepartment of Social Pediatrics, Hospital for Children and Adolescents, Helsinki University Central Hospital, University of Helsinki, P.O. Box 280, 00029 HUS, Helsinki, Finland, kaisa.kivisto@helsinki.fi.
H Alapulli
S Tupola
S Alaluusua
S Kivitie-Kallio

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the oral health and dental neglect of prenatally buprenorphine-exposed 3-year-old children.

methodsThe study consisted of 51 children who as newborns tested positive for buprenorphine in a urine screen. The control group comprised 68 children previously unexposed to narcotics. The dentist examined the children and interviewed their guardians.

resultsBuprenorphine-exposed children exhibited significantly more early childhood caries than did the control group. Caries indices, the number of decayed, missing and filled teeth or tooth surfaces and decayed teeth were greater in the buprenorphine-exposed children than the control children (p = 0.004, p = 0.004, p = 0.001, respectively). In the buprenorphine group, more children showed visible plaque (p = 0.003) and fewer children were caries-free (p = 0.009) than in the control group. The control children's teeth were also brushed more often than the buprenorphine-exposed children's teeth (p = 0.001) and the parents were more involved in their children's tooth brushing than were those in the buprenorphine-exposed group (p = 0.035).

conclusionsMore caries and dental neglect were found in buprenorphine-exposed children than in controls. These findings highlight the importance of routine dental appointments, caries screening and preventive care for children in substance-abusing families.

Indexed as

Opioid-Related DisordersOral HealthPrenatal Exposure Delayed EffectsAdultBuprenorphineChild AbuseChild CareChild, PreschoolDental Care for ChildrenDental CariesDental EnamelDental PlaqueDMF IndexEducational StatusFemaleHumansBuprenorphineNarcotics

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.