ArticleIntensive care medicine2014
Outcome of elderly patients with circulatory failure.
Article in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02849756 (Future of the Older Patients After Intensive Care Unit), which is not on this map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Future of the Older Patients After Intensive Care Unit
Who cites it
18 citing papers in PubMed.
- Observational
- Characteristics, outcomes, and complications among nonagenarian and centenarian patients admitted to the intensive care unit: a scoping review.Critical care (London, England) · 2025Article
- Prognosis of Very Elderly Patients after Intensive Care.Journal of clinical medicine · 2022Article
- ICU-Mortality in Old and Very Old Patients Suffering From Sepsis and Septic Shock.Frontiers in medicine · 2021Article
- Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study.Annals of intensive care · 2020Article
- Early Immunoparalysis Was Associated with Poor Prognosis in Elderly Patients with Sepsis: Secondary Analysis of the ETASS Study.Infection and drug resistance · 2020Article
- Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU.Journal of the American Geriatrics Society · 2019Article
- The association between the APACHE-II scores and age groups for predicting mortality in an intensive care unit: a retrospective study.Romanian journal of anaesthesia and intensive care · 2019Article
- [Intensive care medicine-survival and prospect of life].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017Review
- The status of intensive care medicine research and a future agenda for very old patients in the ICU.Intensive care medicine · 2017Review
- Sepsis and Immunosenescence in the Elderly Patient: A Review.Frontiers in medicine · 2017Review
- Sepsis outside intensive care unit: the other side of the coin.Infection · 2015Review
- Age, risk, and life expectancy in Norwegian intensive care: a registry-based population modelling study.PloS one · 2015Article
- Distinct determinants of long-term and short-term survival in critical illness.Intensive care medicine · 2014Observational
- Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study.Intensive care medicine · 2014Observational
- Characteristics, management and outcomes of critically ill patients who are 80 years and older: a retrospective comparative cohort study.BMC anesthesiology · 2014Article
- Anesthesia and perioperative pain relief in the frail elderly patient.Saudi journal of anaesthesiaReview
- Comparative analysis of survival between elderly and non-elderly severe sepsis and septic shock resuscitated patients.Einstein (Sao Paulo, Brazil)Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe proportion of elderly patients admitted to the ICU is increasing. Mortality rates are known to increase with age but the impact of age on outcomes after circulatory shock has not been well defined.
methodsWe performed a secondary analysis of data from a large randomized trial comparing the effects of dopamine and norepinephrine on outcome in the ICU. Patients were separated into not old (<75 years), old (75-84 years), and very old (≥85 years).
resultsOf the 1,679 patients included in the initial trial, 1,651 had sufficient age data available: 1,157 (70%) were not old, 410 (25%) were old, and 84 (5%) were very old. There were minor differences among the age groups in the APACHE II score calculated without the age component (not old, 17 ± 9; old, 18 ± 9; very old, 19 ± 9; p = 0.047), but SOFA scores were similar (not old, 9 ± 4; old, 9 ± 3; very old, 9 ± 3; p = 0.76). Mortality rates were higher in old and very old patients at 28 days, at hospital discharge, and after 6 and 12 months. Most very old patients were dead at 6 (92%) and 12 months (97%). Mortality rates increased with age in all types of shock. Using multivariable analysis, the risk of death was higher in very old patients as compared to not old (adjusted OR 0.33, 95% CI 0.2-0.56, p < 0.001).
conclusionsAgeing is independently associated with higher mortality rates in patients with circulatory failure, whatever the etiology. By 1 year after admission, most patients 85 years of age and older were dead.
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