Evidence map›Paper›PMID 24132382›Full record

ReviewIntensive care medicine2014

Unrecognized suffering in the ICU: addressing dyspnea in mechanically ventilated patients.

Matthieu Schmidt, Robert B Banzett, Mathieu Raux, Capucine Morélot-Panzini, Laurence Dangers, Thomas Similowski, Alexandre Demoule

3 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02801994 nacompletednot on this mapstarted 2016, after this paper: background citation

Impact of Proportional Assisted Ventilation on Dyspnea and Asynchrony in Mechanically Ventilated Patients

TypeinterventionalSponsorAssociation pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le SommeilRan2016 to 2017Enrolled34ConditionsDyspneaArmsPAV, Puritan Bennett 980 ventilator
NCT04569266 nacompletednot on this mapstarted 2020, after this paper: background citation

Effectiveness of an Exercise Re-training Program on Dyspnea in Patients After Acute Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia in Post-ICU

TypeinterventionalSponsorFondation Hôpital Saint-JosephRan2020 to 2023Enrolled63ConditionsDyspneaArmsSpecific exercise rehabilitation treatment, No specific exercise rehabilitation treatment
NCT05890560 unknown statusnot on this mapstarted 2023, after this paper: background citation

Comparison of the Two-year Efficacy of Three Exercise Rehabilitation Strategies on Dyspnea in Patients Who Presented With Secondary Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2023 to 2024Enrolled120ConditionsDyspnea, COVID-19
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 150 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Observational
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  15. Article
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  18. Review
  19. DYSPNEA AND MECHANICAL VENTILATION: APPLYING PHYSIOLOGY TO GUIDE THERAPY.Transactions of the American Clinical and Climatological Association · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Matthieu SchmidtER10, Université Paris 6-Pierre et Marie Curie, Paris, France.
Robert B Banzett
Mathieu Raux
Capucine Morélot-Panzini
Laurence Dangers
Thomas Similowski
Alexandre Demoule
Sorbonne Université · FRHarvard University · US

Funding

Quantifying a Vital Symptom: Large-scale Inpatient Dyspnea MeasurementR01NR010006 · NINR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BANZETT, ROBERT B · 2007 to 2017
$4.0M
AEROSOL FUROSEMIDE FOR DYSPNEA RELIEF: LABORATORY AND CLINICAL STUDIESR01NR012009 · NINR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BANZETT, ROBERT B · 2011 to 2015
$2.3M
NINR NIH HHS R01 NR010006NINR NIH HHS R01 NR012009
6 · The paper itself

Abstract

backgroundIntensive care unit (ICU) patients are exposed to many sources of discomfort. Although increasing attention is being given to the detection and treatment of pain, very little is given to the detection and treatment of dyspnea (defined as "breathing discomfort").

methodsPublished information on the prevalence, mechanisms, and potential negative impacts of dyspnea in mechanically ventilated patients are reviewed. The most appropriate tools to detect and quantify dyspnea in ICU patients are also assessed. RESULTS/

conclusionsGrowing evidence suggests that dyspnea is a frequent issue in mechanically ventilated ICU patients, is highly associated with anxiety and pain, and is improved in many patients by altering the ventilator settings.

conclusionsFuture studies are needed to better delineate the impact of dyspnea in the ICU and to define diagnostic, monitoring and therapeutic protocols.

Indexed as

AnxietyCritical CareDyspneaHumansIntensive Care UnitsPainPain ManagementPulmonary Gas ExchangeRespiration, ArtificialTidal VolumeVisual Analog Scale

Identifiers

PMID24132382
PMCPMC4117200
OpenAlexW1982114931

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.