ReviewJournal of human hypertension2014
Circulating microRNAs as potential non-invasive biomarkers for the early detection of hypertension-related stroke.
Review in Journal of human hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Association of MicroRNAs With Risk of Stroke: A Meta-Analysis.Frontiers in neurology · 2022Pooled it
- Hemorrhagic Stroke Induces a Time-Dependent Upregulation of miR-150-5p and miR-181b-5p in the Bloodstream.Frontiers in neurology · 2021Article
- Emerging Role of microRNAs in Stroke Protection Elicited by Remote Postconditioning.Frontiers in neurology · 2021Review
- MicroRNA and Cardiovascular DiseasesBalkan medical journal · 2020Article
- MicroRNAs in brain development and cerebrovascular pathophysiology.American journal of physiology. Cell physiology · 2019Review
- Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study.PloS one · 2019Article
- Characterization of Dysregulated miRNA in Peripheral Blood Mononuclear Cells from Ischemic Stroke Patients.Molecular neurobiology · 2018Article
- Genetic Variants in MicroRNAs Predict Recurrence of Ischemic Stroke.Molecular neurobiology · 2017Article
- Epigenetics in Stroke Recovery.Genes · 2017Review
- A Decrease of Brain MicroRNA-122 Level Is an Early Marker of Cerebrovascular Disease in the Stroke-Prone Spontaneously Hypertensive Rat.Oxidative medicine and cellular longevity · 2017Article
- MicroRNAs are associated with blood-pressure effects of exposure to particulate matter: Results from a mediated moderation analysis.Environmental research · 2016Article
- Non-coding RNAs and hypertension-unveiling unexpected mechanisms of hypertension by the dark matter of the genome.Current hypertension reviews · 2015Review
- Role of circulating miRNAs as biomarkers in idiopathic pulmonary arterial hypertension: possible relevance of miR-23a.Oxidative medicine and cellular longevity · 2015Article
- Circulating microRNAs in cardiovascular diseases: from biomarkers to therapeutic targets.Frontiers of medicine · 2014Review
- Transient ischemic attacks: predictability of future ischemic stroke or transient ischemic attack events.Therapeutics and clinical risk management · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension is one of the most important risk and modifiable factors for stroke. Crucial in managing the cerebrovascular damage caused by long-lasting and inadequately treated hypertension is not only lowering arterial blood pressure but also early predicting subtypes of hypertension-related stroke and applying more effective interventions. Accumulating evidence suggested that circulating microRNAs (miRNAs) could be developed as biomarkers for early recognition of the onset of a variety of diseases. The role of miRNAs has been extensively reviewed, involving cardiac hypertrophy, hypertensive heart failure, kidney failure and renal fibrosis. miRNA research in stroke is still in its infancy, although there are few literatures reviewing the role of miRNAs in the processes of hypertension-related stroke. This review summarizes current advances in miRNAs regulation of critical pathogenic process underlying hypertension, ischemic stroke and hemorrhagic stroke, and highlights the potential of using circulating miRNAs as noninvasive biomarkers for the early detection of hypertension-related stroke.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.