ArticleThe ISME journal2014
Genetic diversity of inorganic carbon uptake systems causes variation in CO2 response of the cyanobacterium Microcystis.
Article in The ISME journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 128 citations in OpenAlex.
- Functional and structural insights into cyanobacterial COThe Plant journal : for cell and molecular biology · 2026Review
- Architectural and biochemical advances in understanding microbial COThe Plant journal : for cell and molecular biology · 2026Review
- Competition and interdependence define interactions of Nostoc sp. and Agrobacterium sp. under inorganic carbon limitation.NPJ biofilms and microbiomes · 2025Article
- Microcystin shapes theISME communications · 2025Article
- Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts.Journal of experimental botany · 2024Article
- Selection of photosynthetic traits by turbulent mixing governs formation of cyanobacterial blooms in shallow eutrophic lakes.The ISME journal · 2024Article
- Impact of temperature on the temporal dynamics of microcystin inFrontiers in microbiology · 2023Article
- Preference of carbon absorption determines the competitive ability of algae along atmospheric COEcology and evolution · 2022Article
- Perceived Intensification in Harmful Algal Blooms Is a Wave of Cumulative Threat to the Aquatic Ecosystems.Biology · 2022Review
- Microbial Biofilms Along a Geochemical Gradient at the Shallow-Water Hydrothermal System of Vulcano Island, Mediterranean Sea.Frontiers in microbiology · 2022Article
- Comparative Genomic Analysis Revealed Distinct Molecular Components and Organization of COFrontiers in microbiology · 2022Article
- A comparative study of metatranscriptomic assessment methods to characterize Microcystis blooms.Limnology and oceanography, methods · 2021Article
- Diel Variations of Extracellular Microcystin Influence the Subcellular Dynamics of RubisCO inMicroorganisms · 2021Article
- Phenotypic plasticity of carbon fixation stimulates cyanobacterial blooms at elevated COScience advances · 2020Article
- Effect of COFrontiers in microbiology · 2019Article
- Metatranscriptomic Analyses of Diel Metabolic Functions During aFrontiers in microbiology · 2019Article
- Responses of macroalgae to COEcology and evolution · 2019Article
- Urea Is Both a Carbon and Nitrogen Source forFrontiers in microbiology · 2019Article
- Cyanobacterial blooms.Nature reviews. Microbiology · 2018Review
- Cyanobacteria vs green algae: which group has the edge?Journal of experimental botany · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rising CO2 levels may act as an important selective factor on the CO2-concentrating mechanism (CCM) of cyanobacteria. We investigated genetic diversity in the CCM of Microcystis aeruginosa, a species producing harmful cyanobacterial blooms in many lakes worldwide. All 20 investigated Microcystis strains contained complete genes for two CO2 uptake systems, the ATP-dependent bicarbonate uptake system BCT1 and several carbonic anhydrases (CAs). However, 12 strains lacked either the high-flux bicarbonate transporter BicA or the high-affinity bicarbonate transporter SbtA. Both genes, bicA and sbtA, were located on the same operon, and the expression of this operon is most likely regulated by an additional LysR-type transcriptional regulator (CcmR2). Strains with only a small bicA fragment clustered together in the phylogenetic tree of sbtAB, and the bicA fragments were similar in strains isolated from different continents. This indicates that a common ancestor may first have lost most of its bicA gene and subsequently spread over the world. Growth experiments showed that strains with sbtA performed better at low inorganic carbon (Ci) conditions, whereas strains with bicA performed better at high Ci conditions. This offers an alternative explanation of previous competition experiments, as our results reveal that the competition at low CO2 levels was won by a specialist with only sbtA, whereas a generalist with both bicA and sbtA won at high CO2 levels. Hence, genetic and phenotypic variation in Ci uptake systems provide Microcystis with the potential for microevolutionary adaptation to changing CO2 conditions, with a selective advantage for bicA-containing strains in a high-CO2 world.
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