ArticleAging2013
Aging on a different scale--chronological versus pathology-related aging.
Article in Aging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Article
- Getting the chronological age out of DNA: using insights of age-dependent DNA methylation for forensic DNA applications.Genes & genomics · 2023Review
- PathoClock and PhysioClock in mice recapitulate human multimorbidity and heterogeneous aging.Aging pathobiology and therapeutics · 2021Article
- Article
- Measuring Exercise Capacity and Physical Function in Adult and Older Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- The road ahead for health and lifespan interventions.Ageing research reviews · 2020Review
- A mathematical model reveals sex-specific changes in glucose and insulin tolerance during rat puberty and maturation.Croatian medical journal · 2020Article
- Integrating functional ageing into daily clinical practice.Journal of frailty, sarcopenia and falls · 2019Review
- Heart rate fragmentation: using cardiac pacemaker dynamics to probe the pace of biological aging.American journal of physiology. Heart and circulatory physiology · 2019Article
- Review
- Bridging the Gap between Alzheimer's Disease and Alzheimer's-like Diseases in Animals.International journal of molecular sciences · 2019Review
- Transcriptomics in lung tissue upon respiratory syncytial virus infection reveals aging as important modulator of immune activation and matrix maintenance.Scientific reports · 2018Article
- Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice.Aging · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
In the next decades the elderly population will increase dramatically, demanding appropriate solutions in health care and aging research focusing on healthy aging to prevent high burdens and costs in health care. For this, research targeting tissue-specific and individual aging is paramount to make the necessary progression in aging research. In a recently published study we have attempted to make a step interpreting aging data on chronological as well as pathological scale. For this, we sampled five major tissues at regular time intervals during the entire C57BL/6J murine lifespan from a controlled in vivo aging study, measured the whole transcriptome and incorporated temporal as well as physical health aspects into the analyses. In total, we used 18 different age-related pathological parameters and transcriptomic profiles of liver, kidney, spleen, lung and brain and created a database that can now be used for a broad systems biology approach. In our study, we focused on the dynamics of biological processes during chronological aging and the comparison between chronological and pathology-related aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.